A recent analysis of data from the landmark ASPREE trial revealed that prolonged daily aspirin consumption increased anemia risk by 20 percent in individuals predominantly aged 70 and above. In light of these findings, researchers recommend routine anemia checks for elderly individuals on low-dos
That really was a “no shit, Sherlock” kind of study. Basically every modern-era analysis of risk vs benefit of aspirin for primary prevention of ascvd I have seen has pointed out the number needed to treat vs number needed to harm was at best equal when you take all comers and at worst trending towards harm in some subgroups. There might be some benefit in certain populations when you look at it with stroke, but every single one of these studies I have ever read comments on the increased risk of bleeding. Most of the guidelines already reflect this. I guess it’s a good thing the nih is protecting our tax money by refusing to sink money into studies with mortality as a primary endpoint anymore so they have plenty of cash to throw at studies like this that are splitting hairs academically.
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