When Gravity Fails by George Alec Effinger is a kind of complicated recommendation for this. It features I think the most trans characters I’ve ever seen in one book, the main character’s girlfriend and most of their acquaintances are trans, and the story treats them decently as people with jobs and lives outside of that part of their identity. The problem, if it is one, is that they’re all sex workers. I can’t remember any trans character in the book who isn’t. This fits the story decently as they’re all living in the Budayeen, the entertainment and criminal quarter of an unnamed Middle-Eastern city, the only place where they, and small-time criminals like the protagonist, can exist with a minimum of hassle. But there’s some complicated history and pop-cupture entanglements around being trans and being a sex worker (and the limited other roles historically available to them) which might change how audiences read this forty years later. I honestly have no idea. I quite liked the book, it’s weird in places (for other reasons) but that’s what I read cyberpunk for, and it has a bunch of awesome cyberpunk concepts, a unique setting, and some creative misuses of technology.
The Murderbot books feature a pretty diverse spread of characters, gay, nonbinary, and also people in polyamorous relationships, though that stuff usually doesn’t impact the main plot. Murderbot itself is about as asexual as it’s possible to get which probably explains that a bit. Their tone isn’t super cyberpunk but the themes and concepts very much are.
I think the Gibson short story Johnny Mnemonic or Burning Chrome has a pair of guards, one of whom is trans, but it’s clearly been awhile since I read it. Gibson’s Sprawl books all had a kind of fascination with extending cosmetic surgery past sex and race, identity being as changeable as hairstyle, so it comes up in passing occasionally.