The biggest pain point I see from new players is combat. It’s totally focused on your character, not you as a player. It’s closer to BG3 in combat than modern TES. Every attack rolls dice, and the result is based on that and also your character stats. If your character doesn’t know how to use a sword, you’re not going to hit. If your character is tired (low stamina) you’re not going to hit. The game let’s you pick up a weapon you don’t know how to use and try to use it without warning, but it won’t turn out well.
The most infamous example of this is you can get a dagger early. Then players will run from the first town, using all their stamina, then try to fight an enemy. They will then fail to hit at all and think it’s the fault of the game, but it’s really just a lack of understanding of the systems. The game does fail to explain the consequences of this though.