Python's public API changes subtly, so minor changes in Python version can lead to massive changes in the version of dependencies you use.
A few years ago we developed a script to update Cassandra on Python 2.7.Y. Production environment used Python 2.7.X (it was 5 patch releases earlier).
This completely changed the cassandra library version. We had to go back 15 patch releases which annoying resulting in a breaking change in the Cassandra libraries API and wouldn't work on the dev environments Python.
Python 3 hasn't solved this, 2 years ago I was asked to look at a number of Machine Learning projects running in docker. Upgrading Python from 3.4 to 3.8 had a huge effect on dependencies and figuring out the right combination was a huge pain.
This is a solved problem in Java, Node.js has the same weakness but their changes to language spec are additive so old code runs on new releases (just not the inverse). Ruby has exactly the same issues as Python