@aheadofthenerve@neuromatch.social
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aheadofthenerve

@aheadofthenerve@neuromatch.social

BRAIN K99/R00. HPC experimental & computational systems neuro. Ephys4life.
Postdoc @NUFeinbergMed with John Disterhoft and co-mentor Sara Solla, PhD from MIT with Matt Wilson, BS from Carnegie Mellon 🔬🧠🐀🌈

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elduvelle, to random
@elduvelle@neuromatch.social avatar

“Are you enjoying Duo Mobile” … 🤔

How can I tell you… I enjoy it as much as having to brush my teeth after each meal or emptying the dishwasher..
do I wish I didn’t have to use it at all? YES
can I do without it at the moment? Unfortunately NO because for some reason our lives are governed by the ever-present but really, really small risk that someone might want to hack my work email..

(Duo mobile is one of these #Authenticator apps)

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@elduvelle i refuse to install Duo mobile and still make all authenticator send me a text, which is annoying, BUT AT LEAST I DONT HAVE DUO MOBILE

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

me: WHY ISNT THIS MODEL WORKING
also me, 40min later: oh lol wanted a value to be .00000055 but somehow deleted the decimal so it was 00000055 which is 55 lololol stabs self

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

got an email today addressed to two Drs and then to "Hannah." The other Drs are my PI (senior prof) and a research prof. Is this a seniority thing or did I just get .... not-doctored

https://www.theswaddle.com/why-women-academics-with-ph-d-s-are-often-not-called-dr

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

wanted to clarify that yes of course the other two Drs are men

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@justafrog I responded with this PS:

PS: Re the salutation, I am completely fine going by Hannah but I noticed you addressed Craig and John using Dr Weiss and Dr Disterhoft, respectively, and I wanted to be clear I am also a Dr :)

and in the next email I got doctor-ed ;)

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

my sanity is hanging on by increasingly unhinged commit messages

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

ok @MiniscopeTeam folks and users-- the extra EWLs I used to order (https://www.edmundoptics.com/p/25mm-ca-a-25h0-corning-varioptic-variable-focus-liquid-lens/3668/) no longer exist. where can I get them?? TY

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@jonny nope

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@jonny thank you!

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

as long as I have the attenion of the HPC folks-- what are we doing these days when bootstrapping for place cell mutual info? shuffling positions and keeping spike times (and thus ISI) constant, or shuffling spike times? Seen both in papers and unsure if there is a consensus

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@elduvelle_neuro

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@elduvelle_neuro yeah, rn I am circularly shifting the position data relative to spikes (to keep ISI the same-- so equivalent to what you wrote), but have also seen actually shuffled position (as opposed to shifted) as well as shuffled spike times. UG!
I'm writing up the paper now so hope to have a preprint out soon(ish). All the data etc is there but it's dragging on fiddly details like how to shuffle that won't really impact the conclusion but I want it to be as bullet proof as possible, obviously

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@elduvelle_neuro yes shifting position is same as shifting cell times. but I have def also seen shuffling position or even spike or calcium transient times

ie (from a VERY quick search) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595956/
https://www.pnas.org/doi/full/10.1073/pnas.2221141120
https://www.nature.com/articles/nn.3329#Sec2
these 3 shuffle calcium transient times

https://grewelab.org/wp-content/uploads/2023/02/Przemyslaw-et-al.-2022.pdf
shuffles cell identities

https://www.sciencedirect.com/science/article/pii/S0306452218301088
shuffles position bins and/or firing rate bins

Etc. lol

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

machine learning folks: i am training 1 model per rat on that rats recording data to decode that rat's behavior. Each rat has a different number of cells recorded. Is it kosher to use different parameters for different rats (ie some or all of: learning rates, temps, iterations, etc) to make the models? even if I want to compare the models later?

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@hosford42 @jonny yes, correct! neurons (and behavior for that matter) can't be pooled across animals so you need a different model per animal. but since inputs are also relatively different per animal (ex one animal has 800 cells and another has 100) having fixed hyperparameters doesn't make for the best models for each animal

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@hosford42 @jonny great, thank you!

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@jonny @hosford42 the answer is always make a grid search that leads you to a month more of grid searches

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

can someone at @CosyneMeeting tell me what "Mind Matching (Neuromatch)" is gonna be so I know whether to rush over? TY!

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

Any other wet lab folks packing for
@CosyneMeeting ?

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

hi ca imaging folks, what spatial corr threshold are we using these days to track cells across days? I've seen everything from .4-.7 and above. citations also appreciated

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

i legit think something is wrong with this rat

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

pick ur fighter

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

if there is no such thing as dumb rats only dumb experimenters I've been very very very dumb during the duration of training this animal

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@jonny only smart rats tho ;)

aheadofthenerve, to random
@aheadofthenerve@neuromatch.social avatar

when you email your mentor all excited about a finding and say "Maybe I am overreacting but it feels big??? Feel free to talk me down ;))) (or up!!)"

and she responds "This is BIG!!! you are not deluding yourself."

AHHHHHHH

aheadofthenerve,
@aheadofthenerve@neuromatch.social avatar

@jonny waiting for the other shoe to come hurling down

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