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cross-posted from: literature.cafe/post/10359040...

This study has identified the anterior cingulate cortex (ACC) as a key area in the brain responsible for sensory hypersensitivity in autism spectrum disorders. Utilizing a mouse model with a Grin2b gene mutation, heightened neural activity and connectivity in the ACC was observed. Suppressing this hyperactivity normalized the...

A breakthrough in hydrogen production has been achieved by a Japanese research team, reducing the need for iridium by 95% without compromising efficiency, paving the way for sustainable, large-scale hydrogen energy solutions.

A cohort study found that individuals who engaged in mentally stimulating jobs during their 30s to 60s were less likely to develop mild cognitive impairment (MCI) and dementia after turning 70, highlighting the importance of cognitive stimulation during midlife for maintaining cognitive function in old age. [It is important to...

The engineering of artificial cells requires a reconfigurable cytoskeleton that can organize at distinct locations and dynamically modulate its structural and mechanical properties. This study combines peptide self-assembly with DNA programmability to realize a synthetic cytoskeleton in droplets showing that programmable...

This study describes the identification of an antibiotic class acting via LpxH, involved in lipopolysaccharide synthesis having potent in vivo efficacy against bloodstream infections caused by the critical Gram-negative pathogens E. coli and Klebsiella pneumoniae. Further development of this class of antibiotics could make an...

This study attempts to identify the “protective” genetic factors that can modify or reduce the effect of APOEε4 on Alzheimer’s disease risk and to identify new pathogenic mechanisms, proteins, and pathways that inform development of therapeutic targets and diagnostics....

Brief anger can temporarily impair blood vessel function, potentially heightening heart disease and stroke risks, finds new study in the Journal of the American Heart Association.

Scientists have identified a new hybrid brain cell, sharing attributes of neurons and astrocytes. These cells can release neurotransmitters and may influence conditions like epilepsy and memory consolidation.

cross-posted from: lemmy.world/post/14590664...

A Texas farm worker contracted H5N1 from dairy cattle, indicating a new route of transmission for the virus, which has a high mortality rate and diverse symptoms in humans. The United States’ Centers for Disease Control and Prevention (CDC) has issued a health alert after the first case of H5N1 a

This study reveals how life’s complexity could originate from simple RNA molecules on early Earth. Through experiments demonstrating RNA’s recycling and replication abilities under conditions such as low salinity and high pH, the research suggests life could emerge from minimal molecular sets in environments akin to volcanic...

This study shows that a ketogenic diet slows early Alzheimer’s memory loss in mice, in which the molecule beta-hydroxybutyrate (BHB), plays an important role thus offering hope for its application in human ageing and cognitive health....

“Researchers have successfully transformed CO2 into methanol,” reports SciTechDaily, “by shining sunlight on single atoms of copper deposited on a light-activated material, a discovery that paves the way for creating new green fuels.”...

Innovative research on hydrogen production from geological sources could significantly impact the sustainable energy landscape, offering a low-carbon alternative to current methods....

Innovative research on hydrogen production from geological sources could significantly impact the sustainable energy landscape, offering a low-carbon alternative to current methods....

Trees are struggling to sequester heat-trapping carbon dioxide (CO2) in warmer, drier climates, meaning that they may no longer serve as a solution for offsetting humanity’s carbon footprint as the planet continues to warm, according to a new study led by Penn State researchers.

This study has used publicly available MS/MS spectra for bile-acid-selective ion patterns to identify thousands of polyamine bile amidates. It highlights the existence of many more bile acid modifications than previously recognized and the value of leveraging public large-scale untargeted metabolomics data to discover...

Metformin is a widely prescribed anti-diabetic medicine that also reduces body weight. There is ongoing debate about the mechanisms that mediate metformin’s effects on energy balance. This study shows that metformin induces the formation of hunger-reducing metabolite N-lactoyl-phenylalanine (Lac-Phe), a byproduct of muscle...