I went into Nextcloud expecting to have a terrible experience, especially with slow syncing speeds which seem to be a persistent complaint.
I was pleasantly surprised that syncing for my 3TB dataset which is a mix of documents, design work, photography, and videos, has worked just as quickly as Syncthing and Resilio Sync on local gigabit network.
I run Nextcloud AIO on TrueNAS SCALE in a systemd-nspawn container with ncdata bind mount from NVME and the rest of the data using External Storage plugin locally.
I only use Nextcloud for Memories (photo app), file syncing and file sharing, so my usage of it is relatively light.