there should be a file in the ARCADE folder called miyoogamelist.xml; this should contain XML entries for every ROM in the folder; the file names in this file should match the ROM files in the ARCADE folder (such as outrun.zip).
Cores
Most of the time, it's better to stick with the default core, but there are a couple of options for choosing a different one.
Enable the Expert tab (Apps -> Tweaks -> User Interface -> Show expert mode): with Genesis Plus installed, Mega Drive/Genesis games will show up in the Expert section as playable with that core
use Game List Options (GLO): in the standard game list, bring up GLO by pressing Y, and choose a different core; this will only affect the highlighted game and is useful when there are a few games that don't perform as well with the default core.