The car mic and one of the right side speakers stopped working. The ota updates also stopped arriving, and toyota stopped sending me emails about where my car had been / how long it was driven. The emergency button which calls the toyota help line is also broken now.
There were no warnings from my car at all after i pulled the fuse.
There's some forum posts about rewiring the speaker back into the system - apparently you only need an extra plug, a little bit of wiring skills, and access through the glove box to get it working again. I havent personally done it yet, but ill get around to it at some point.