This article from the guardian indicates the need to develop and produce synthetic coffee in the future after climate change has ravaged land reserved for coffee production.
Honestly while coffee’s days are likely numbered, stimulants will likely only be further developed in the lab to be more finely honed to enhance potential human productivity levels and, hopefully, be made safer for human consumption.
Stimulants are necessary particularly to modern militaries and the usage of stimulants in a wartime context have been well documented since WWII.
Given the important role stimulants play in both modern capitalism and modern warfare, it’s unlikely we’ll see a “Stimulopocalypse” any time soon.
That said, the world you allude to might look somewhat like the world awakened by the Knocker-Up, although really it’s more likely all aspects of human life would simply slow down without stimulants.