Tapentadol is a centrally acting analgesic medication used primarily for the management of moderate to severe pain. It is structurally similar to tramadol but has a more potent analgesic effect. Tapentadol works by binding to mu-opioid receptors in the central nervous system and inhibiting the reuptake of norepinephrine. Tapentadol is used to relieve moderate to severe pain, such as pain from injuries, surgeries, chronic conditions like osteoarthritis, neuropathic pain, and cancer pain. Tapentadol acts as both a mu-opioid receptor agonist and a norepinephrine reuptake inhibitor (NRI). This dual mechanism of action provides pain relief through two different pathways, potentially leading to improved efficacy and reduced side effects compared to traditional opioids.
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