There’s some that are really good at detection, and a very small number that are good at prevention.
Usually, detection also means prevention, unless we’re talking about norton and mcaffee, which sometimes don’t detect anything until after the malware has already done its damage.
Comodo firewall configured like Cruelsister recommends along with bitdefender free, kaspersky (any edition with the firewall turned off), or MSD with configure defender on MAX is pretty good. Covers everything between comodo FW and one of those other three.
But those three conventional antivirus programs might start sucking at some point down the line. for as long as I’ve been using it, comodo FW has always been a good choice to pick up the slack of whatever realtime scanner you choose.