That's an oddly terrifying thought. Which makes me wonder... you know how stars sometimes get ejected from their parent galaxies and end up free-floating through the universe, all on their own?
Imagine if a star got ejected from one of those galaxies, managed to travel far enough away the parent couldn't be seen without advanced telescopes, and then life evolved on one of its planets.
That civilization would grow up in a world without stars. The sky at night would be pure black nothingness, except for the pinprick light of any other planets in the system. And then, after assuming their solar system was the entirety of existence for thousands of years, only in their culture's equivalent of the 1960s do they see the first light of other suns.