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What the hell about this woman's background makes her suited to be an "independent investigator" of issues?

https://en.wikipedia.org/wiki/Hilary_Cass

There's literally nothing here that ties into any of the fields that are relevant. Her specialization is all in developmental and mental disabilities in high-support-need younger children.

"Independent" evidently means "so far out of her lane that she can't see her lane on this side of the horizon."

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"Cis doctor who trained in the 1980s—with a specialization in unrelated fields—wants to institute additional barriers to access for people."

Where have I heard that before.

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Also if this particular analysis is true, and I have no reason to doubt it, then I have to also agree with this criticisms analysis.

This is an area where blinding is extraordinarily difficult, if not impossible, to do ethically. Blinding is rarely used in social science in part for exactly this reason.

You aren't working with small groups of inbred mice here.

https://transactual.org.uk/blog/2024/04/11/press-release-the-cass-review-is-bad-science-and-should-not-be-taken-seriously-by-policymakers/

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Anyways, some responses.

Horton, C. (2024). The Cass Review: Cis-supremacy in the UK’s approach to healthcare for trans children. International Journal of Transgender Health, 1–25. https://doi.org/10.1080/26895269.2024.2328249

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Dr. Hane Maung, Response to the Cass Review, GenderGP. This also emphasizes the problem with focusing on blinded RCTs.

https://www.gendergp.com/response-to-the-cass-review/

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Our initial response to the publication of the Cass Review 10.4.24, Scottish Trans

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On the RCT comment: this appears to be a common concern. A user on reddit put together this.

https://www.reddit.com/r/skeptic/comments/1c1i6qa/englands_cass_report_rejected_all_evidence_on/

At least one of those highlighted as "high risk of bias" due to "lack of control group" and "no blinding" was probably this study…

Joseph et al. "The effect of GnRH analogue treatment on bone mineral density in young adolescents with gender dysphoria: findings from a large national cohort" https://doi.org/10.1515/jpem-2019-0046

Which, uh. I question what would have passed muster here.

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Transphobic report by UK pediatrician Hilary Cass released, LA Blade

https://www.losangelesblade.com/2024/04/10/transphobic-report-by-uk-pediatrician-hilary-cass-released/

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Cass Review out of step with high-quality care provided in Aotearoa, Professional Association for Transgender Health Aotearoa (PATHA)

https://patha.nz/News/13341582

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Cass Review out-of-line with medical consensus and lacks relevance in Australian context, Equality Australia

https://equalityaustralia.org.au/cass-review-out-of-line-with-medical-consensus-and-lacks-relevance-in-australian-context/

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Trans Safety Network, TSN statement on Cass Review Final Report

https://transsafety.network/posts/tsn-statement-on-cass-final-report/

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UK: Cass review on gender identity is being 'weaponised' by anti-trans groups, Amnesty International

https://www.amnesty.org.uk/press-releases/uk-cass-review-gender-identity-being-weaponised-anti-trans-groups

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Not directly referencing, but related to the conclusions and the behavior of the NHS.

Gendered Intelligence, NHS England delays puberty suppressing treatments

https://genderedintelligence.co.uk/news/15-nhs-england-delays-puberty-suppressing-treatments

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LGBT+ Liberal Democrats, Initial Statement on the Cass Review

https://lgbt.libdems.org.uk/news/article/initial-statement-on-the-cass-review

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Gemma Stone, Spare a Thought for Hilary Cass, Novara Media

Even those involved in the review have expressed dismay at how it was conducted. Cat Burton, chair of the Gender Identity Research & Education Society, one of the organisations consulted by the Cass review team, took to X/Twitter to say that “after three discussions it was obvious that the review had been written before we started. She [Hilary Cass] totally discounted evidence from trans people from the basis of knowledge or lived experience.”
Cass also suggests that the rate at which young people move from puberty blockers to subsequent hormone treatments may, as anti-trans groups have warned, prove puberty blockers help cement a trans identity in these youth. Her data for this is the fact that in two (2) studies, nearly all trans youth prescribed blockers went on to take hormones. Of course, this finding could just as easily suggest that puberty blockers are being prescribed very precisely – a possibility Hilary Cass does not entertain for even a second.
More worryingly still, many of Cass’s conclusions are based on evidence that does not corroborate, or in some cases, directly contradicts her findings. For example, her recommendation of an intermediate service is based on the idea that brains don’t reach maturity until 25 – a notion that Dean Burnett, a neuroscientist and the author of The Idiot Brain describes as “guff based on hearsay, misunderstanding of neuroscience or wilful ignorance”.

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Nicole Lee, Activist groups raise concerns over “deeply flawed” Cass Review on transgender healthcare, gcn (gay community news)

https://gcn.ie/concerns-cass-review-transgender-healthcare/

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Rowan, Milo, and Luci. The Cass Review Needs To Be Thrown Out Entirely, This Is Why. What The Trans.

https://whatthetrans.com/cass-review/

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Trans Healthcare Action. We cannot allow the deeply-flawed Cass Review to dictate the future of trans healthcare in Ireland.

https://www.instagram.com/p/C5l_QGGvpSf/

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Brynn Tannehill. The Cass Review heralds how all trans medicine will die. Los Angelas Blade.

https://www.losangelesblade.com/2024/04/15/the-cass-review-heralds-how-all-trans-medicine-will-die/

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Gemma Stone. The 32 things The Cass Review recommends and why they are concerning. Trans Writes.

https://transwrites.world/the-cass-review-recommendations/

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Jules Roscoe. Review Used By UK to Limit Gender Affirming Care Uses Images of AI-Generated Kids. 404 Media (@404mediaco ).

https://www.404media.co/uk-gender-affirming-care-ai-generated-children/

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Dylan Naylor and Willow Parker. Cass report: ‘Here’s why politicians should not treat it as gospel’. Labour List.

https://labourlist.org/2024/04/hilary-cass-trans-report-final-review-lgbt-labour-policy-manifesto/

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Gillian Branstetter. Between Reproductive Past and Trans Future. The Autonomy.

https://autonomy.substack.com/p/between-past-and-future

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Not about the Cass review, but talking about the standards of evidence.

Brik et al. Trajectories of Adolescents Treated with Gonadotropin‐Releasing Hormone Analogues for Gender Dysphoria. Archives of Sexual Behavior (which is… something). 2018.

Even the journal that Zucker used to be the editor in chief of, that has a history of anti-trans bias, has published things that say "this would answer questions but would be considered unethical."

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Han Tiernan. Over 130 Irish academics sign open letter criticising Cass Review on transgender healthcare. gcn.

https://gcn.ie/irish-academics-letter-criticising-cass-review/

The open letter in question: https://sway.cloud.microsoft/pFNJFRo9BM6LChR0?ref=Link&loc=play

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Cal Horton. Ten Dangerous Cass Review Recommendations. Growing Up Transgender.

https://growinguptransgender.com/2024/04/16/ten-dangerous-cass-review-recommendations/

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Trans Learning Partnership. The Trans Learning Partnership has developed policy statements on a range of issues affecting the trans community.

https://www.the-tlp.org.uk/policy-statements/

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In the Misc category:

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Kaylin Hamilton. The UK’s Cass Review Is Already Harming Transgender Young People. Prism & Pen.

https://medium.com/prismnpen/the-uks-cass-review-is-already-harming-transgender-young-people-0fb41b1aeaeb

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Gideon, M-K. The Cass Review Into Gender Identity Services for Children - Part 1. Gideon M-K: Health Nerd.

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Carnell, Henry. The UK’s New Study on Gender Affirming Care Misses the Mark in So Many Ways. Mother Jones. 10 May 2024.

https://www.motherjones.com/politics/2024/05/cass-review-transgender-health-care-nhs-gender-affirming-care/

“It’s a bad faith claim that we don’t have enough evidence for pubertal suppressants or gender-affirming hormones,” says Keuroghlian, who has worked with over 2,000 trans and gender-diverse patients in their career. “Gender-affirming medical interventions have been used for adolescent gender dysphoria for decades, and we have a large body of evidence linking them to improved mental health outcomes,” says Turban.
Perhaps because of the loose use of terminology, the Cass report describes some gender-medicine research as “poor” even though those same studies were rated “moderate” or “high quality” by reviewers at the University of York. The studies downgraded by Cass all demonstrated the efficacy of gender-affirming medical interventions. On the other hand, other studies that didn’t come to such strong conclusions in favor of intervention were not similarly downgraded.
More broadly, Keuroghlian and McNamara both argue that Cass’ conclusions undermining the observational studies is itself a form of bias. “The review’s conclusions are discriminatory,” says Keuroghlian. “It’s an intentional misapplication of science to deny a minoritized group access to medically necessary evidence-based care.” “Any deviation from basic principles of evidence-based medicine suggests bias,” says McNamara.

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Horton, Cal. Social Transition, Puberty Blockers, and the Cass Review (Podcast Transcript). What the Trans. 7 May 2024.

https://whatthetrans.com/social-transition-puberty-blockers-and-the-cass-review-podcast-transcript/

It found that trans children who were supported and able to socially transition in childhood, had positive levels of mental health, depression and anxiety, levels of mental health similar to their cis peers. This was in direct contrast to research at the same time from populations of trans children and adolescents who had not been supported to socially transition, where high levels of depression, anxiety, suicidal ideation or suicide attempts were common. This ground-breaking finding that supported trans children have good levels of mental health is reported by the York systematic review thus “The study found no significant difference in depressive symptoms compared with population averages”. Do you see how the study’s own findings have been distorted to make it sound as though the study result is inconclusive?
Bizarrely they adopt a definition of social transition that is in no way standard, including children who only change appearance or clothing, in order to justify inclusion of a 2013 study in which no youth actually socially transitioned according to today’s understanding of this term.
Being trans is seen as inherently a bad outcome. It doesn’t matter if you are a happy trans teenager, or a healthy trans adult. This is a worse outcome than being a cis adult. The Cass Review utilises HRT to justify this eugenicist bigotry. Trans people, the Cass Review argues, are more likely than cis people to require ongoing HRT – life-long medication. Therefore, the Cass Review argues, policies that can limit and reduce the number of trans people are medically speaking, morally justified.

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