I thought I’d heard one defense that goes if it’s theoretically possible to simulate an entire universe, which I understand it is, then it’s just statistically waaaaaay more likely that we’re in a simulated universe. There’s only one real one (excepting multiverse stuff), and potentially infinite simulated ones.
I don’t remember where I heard this though, and I am a self-admitted idiot, so it’s extremely possible I’m extremely wrong.