As part of an analysis of how U.S. District Court for the Southern District of Florida Judge Aileen Cannon, reports from her courtroom show a judge who is both “prickly” and" insecure" and often has trouble understanding what lawyers from both sides try to explain to her....
Her remarks were straightforwardly true. A Jew, an Irish person, a Traveller and a Black person walk into a bar. Who gets racially profiled before they’ve even ordered a drink?
Yes Jews and Irish people and Travellers will likely experience racism at times throughout their lives. Only Black (or brown) people will experience racism just existing in a white society, just walking down the street, regardless of their clothing or their speech or their cultural practices.
It’s like, women experience sexism always. Gay men only experience homophobia in contexts where their sexuality is known. Visible minority status is a thing.
I would like to know if there is something like iPhone “True Tone” or Samsung “Adaptive Color Tone” in AOSP or if there are alternatives to install....
I’ve been enjoying Kagi, although it also proxies google and others, and you have to pay for it, and I was dismayed to read on Lemmy recently that the CEO may be a sea lion. So yeah, the search for good search continues I suppose
I was pleasantly surpsied by how much audio has improved on Linux when I came back to it this year with Ubuntu studio. Reaper or Bitwig are the way to go. Plugins are the main problem, bridging works OK apparently, but there are some decent native options too
Why is colorectal cancer increasing among young people?
Colon and rectal cancers share many similarities and are typically lumped into one category, called colorectal cancer. Studies, however, show that the increase in diagnoses is mainly driven by a rise in rectal cancers and cancers found in the left, or distal, side of the colon, near the rectum. “That maybe provides an important clue for understanding what might be going on,” said Caitlin Murphy, an associate professor and cancer researcher at UTHealth Houston.
Colorectal cancers in younger people also tend to be more aggressive, and they are often found at a more advanced stage, Dr. Murphy said. But most people affected by early-onset colorectal cancer are too young to be recommended for routine cancer screenings, which have helped decrease rates in adults over 50. In 2021, the U.S. Preventive Services Task Force reduced the recommended age for starting colorectal cancer screening by just five years — from 50 to 45.
A vast majority of colorectal cancer diagnoses are still made in people 50 and older. The American Cancer Society predicted last year that roughly 153,000 new diagnoses would be made in the U.S. in 2023, of which 19,550 would be in people younger than 50. But millennials born around 1990 now have twice the risk of colon cancer compared with people born around the 1950s, while millennials’ risk for rectal cancer is about four times higher than that of older age groups, according to a study published in the Journal of the National Cancer Institute. That means diagnoses are likely to “continue going up as these higher-risk generations age,” Dr. Murphy said.
When cancer is found at a younger-than-usual age, doctors usually suspect that genetic mutations may be to blame. And some molecular studies suggest that tumors in early-onset colorectal cancers do have different mutations driving the cancer compared with tumors in older adults. Another piece of evidence that there is a genetic component: It is clear that having a first-degree relative who had colorectal cancer — or even a precancerous polyp — can increase your risk, Dr. Cecchini said. But genetic changes do not explain the full picture, he said.
Some research has linked lifestyle and dietary changes to increased rates of colorectal cancer in both young people and older adults. Recent generations have consumed more red meat, ultraprocessed foods and sugary beverages, and have been known to binge drink more frequently; between 1992 and 1998, cigarette smoking also increased before declining again, while physical activity has continuously declined for decades. All of these factors — along with the rise in obesity rates since the 1980s — are associated with cancer risk. But once again, none of them fully account for the increase in early-onset colorectal cancer.
“For a lot of these risk factors, like smoking, you have to be exposed for long periods of time before the cancer develops,” said Dr. Andrea Cercek, a co-director of the Center for Young Onset Colorectal and Gastrointestinal Cancers at Memorial Sloan Kettering Cancer Center. And many patients in their 20s and 30s do not even fit in these risk groups, she said. “Many of our patients are athletes,” she said. “Many of them were never heavy, not even in childhood.”
Experts are beginning to investigate if there are other environmental drivers of early-onset cancer. For instance, some small studies have hinted at the idea that people who develop colorectal cancer at an early age have an imbalance of “good” and “bad” bacteria in their gut. Researchers are not only looking at antibiotic use, which can alter the gut microbiome, but also nonsteroidal anti-inflammatory drugs that are used as painkillers, proton pump inhibitors that are used to counter stomach acid issues and several psychiatric medications that may be absorbed through the intestinal lining and have increased in use in recent decades, Dr. Cercek said.
Some experts believe exposure to toxic chemicals in the environment may also be to blame. “There’s patterns of environmental exposures by geography, by race, by sex, by all the things that we know colorectal cancer rates also differ by,” Dr. Murphy said.
For instance, for many years, the rates of colorectal cancer diagnoses were highest among non-Hispanic Black people, but research shows that these cancers increased more among non-Hispanic white people in the 1990s and early 2000s, Dr. Murphy said. Now, both groups have fairly similar rates of cancer. “Does this mean that white people are now being exposed to something that Black people have been exposed to for many, many years? We just don’t know yet,” Dr. Murphy said.
There are also geographic disparities in the increase in cancer, with experts seeing more cases emerge in cities and towns along the Mississippi River, in Southeastern states and in Appalachia, which may be explained by occupational exposures to trace elements like arsenic, chromium, and nickel, which are often used in coal production, chemical plants and other industries in those regions. So-called forever chemicals like per- and polyfluoroalkyl substances, better known as PFAS, have been linked to other cancers and could also be driving some of the increase in early-onset colorectal cancer.
“I don’t think there’s going to be one smoking gun that explains everything,” Dr. Murphy said. “It’s a whole bunch of things.”
The geneticist Jim Wilson, at the University of Edinburgh, was shocked by the frequency he found in the U.K. Biobank, an anonymized research database: One in 7,000 people, according to his unpublished analysis, was born to parents who were first-degree relatives—a brother and a sister or a parent and a child. “That’s way,...
Fun fact, Charles Darwin married his cousin. It used to be a more common among white Britons (and other Europeans, especially royalty lol), but it’s rare now. It is indeed quite common among Britons of Pakistani heritage, buts it’s becoming rarer. And the risk of genetic defects is actually quite small. I don’t think it can be considered incest when its legal.
There is a theory that the reduction in cousin marriage in Europe reduced the power of clan groupings and led to the more indivualistic liberal culture we have now, with both good and less desirable effects (basically, more freedom but weaker communal bonds)
Yeah, you don’t even have to jailbreak it, you can just install it alongside the kobo software, then you can keep both. It’s a bit fiddly to set up but not too bad github.com/…/Installation-on-Kobo-devices
Koreader is available from the Play store if you have an android phone, you can try it out first. Its very customisable, I spend hours tweaking the settings because that’s my idea of fun 😂
I love gaming on the go so I’ll put in a vote for the GBA, which has quite a few NES and SNES conversions.as well as soke great games in it’s own right
I just hit 10 hours in Earthbound on my Anbernic RG280V. I’m looking forward to trying some more SNES games once I’m finished (Super Mario World, Street Fighter Turbo II, Zelda: Link to the Past, etc.)....
Other day I was listening to piso 21 – a Colombian music group – on my Ubuntu, and their Ubuntu album came to queue. Seeing this album cover inspired me to make this meme. hope you all like it....
After buying the Board, the case, membranes, and buttons, you’re probably looking around $85 for a USB c rechargeable Gameboy with a ips screen. Not a bad value.
The Dutch minister of Defense is furious about the leaking of a memo that confirms israel does not have a plan in Gaza and is trying to maximize civilian casualties.
Israel “intends to deliberately cause massive destruction to infrastructure and civilian centers” while taking large numbers of civilian casualties for granted. That violates the laws of war, the memo states.
I guess you’re arguing the memo only accuses them of intending to destroy “civilian centres”, not civilians. But "“taking large numbers of civilian casualties for granted” is part of the intent. Israel is the arsonist who knows there are children sleeping in the house.
My view is that the Dutch are, in diplomatic language, saying that.
'Confused' Judge Cannon needed concept explained 'slowly' to her in court by lawyers: NYT (www.rawstory.com)
As part of an analysis of how U.S. District Court for the Southern District of Florida Judge Aileen Cannon, reports from her courtroom show a judge who is both “prickly” and" insecure" and often has trouble understanding what lawyers from both sides try to explain to her....
We hebben een serieus probleem - Why is Dutch so funny to English speakers? (www.edwest.co.uk)
Diane Abbott readmitted as Labour MP after race row probe (www.bbc.co.uk)
True Tone / Adaptive Color Tone for AOSP
I would like to know if there is something like iPhone “True Tone” or Samsung “Adaptive Color Tone” in AOSP or if there are alternatives to install....
Nicotine rebalances NAD+ homeostasis and improves aging-related symptoms in male mice by enhancing NAMPT activity - Nature Communications (www.nature.com)
The Man Who Killed Google Search (www.wheresyoured.at)
Edward Zitron has been reading all of google’s internal emails that have been released as evidence in the DOJ’s antitrust case against google....
Eww, Copilot AI might auto-launch with Windows 11 soon (www.pcworld.com)
More Young People Than Ever Will Get Colorectal Cancer This Year (www.nytimes.com)
Neurodegenerative disorders linked to higher brain acidity (www.newsweek.com)
[Louis Rossmann] Blizzard locks you out of account if you don't agree to new terms; no ownership, forced arbitration (www.youtube.com)
Shooting and blast reported at concert hall near Moscow (www.theguardian.com)
DNA Tests Are Uncovering the True Prevalence of Incest (www.theatlantic.com)
The geneticist Jim Wilson, at the University of Edinburgh, was shocked by the frequency he found in the U.K. Biobank, an anonymized research database: One in 7,000 people, according to his unpublished analysis, was born to parents who were first-degree relatives—a brother and a sister or a parent and a child. “That’s way,...
Thank you American software (lemmy.today)
In Loving Memory of Square Checkbox (tonsky.me)
How Britain sobered up (www.spectator.co.uk)
What Amazon Kindle? Here's an Open Source eBook Reader (itsfoss.com)
ProtonMail and SimpleLogin emails will be blocked from registering on websites (github.com)
This makes me 😭...
Australian expert ‘over the moon’ to have helped rescue 41 men trapped by tunnel collapse in India (www.theguardian.com)
If forced to choose one retro console forever what would you choose and why?
English rule (lemmy.blahaj.zone)
What's everyone playing?
I just hit 10 hours in Earthbound on my Anbernic RG280V. I’m looking forward to trying some more SNES games once I’m finished (Super Mario World, Street Fighter Turbo II, Zelda: Link to the Past, etc.)....
what's your ubuntu? (discuss.tchncs.de)
Other day I was listening to piso 21 – a Colombian music group – on my Ubuntu, and their Ubuntu album came to queue. Seeing this album cover inspired me to make this meme. hope you all like it....
Funny Playing's New FPGA GameBoy Color (funnyplaying.com)
After buying the Board, the case, membranes, and buttons, you’re probably looking around $85 for a USB c rechargeable Gameboy with a ips screen. Not a bad value.
Dutch embassy warned that Israel uses "disproportionate force" in Gaza (nltimes.nl)
The Dutch minister of Defense is furious about the leaking of a memo that confirms israel does not have a plan in Gaza and is trying to maximize civilian casualties.