In my case, the heat pump is in the basement. So in the summer it's great. It dehumidifies and cools the basement. However in the winter, it's still cooling the basement. So the gas furnace kicks on to heat the basement back up. There's a push-pull there.
However, I have solar, and an excess of electricity credits from it.
So what I've done is put it in high-demand mode which uses more electricity and less heat pump, reducing the push-pull issue.
In the summer I'll put it back in pure heat pump mode.
It makes you allergic to all mammalian meat and potentially other products made from mammals. Outside of the allergic reaction (including anaphylaxis) I wasn't able to find any other negative effects.
oh, I just ran across this:
According to survey results presented at the American Academy of Allergy, Asthma, and Immunology's (AAAAI) Annual Meeting, some alpha-Gal Syndrome patients have a wide range of seemingly new symptoms, such as those involving the cardiovascular, nervous, and motor systems. Furthermore, some patients reported a wide range of mental health issues, such as anxiety, depression, fatigue, poor memory, irritability, sleep disturbances, etc.