@vantablack a really popular rave forum which I was a mod on split its domains because the admin took on Google ads and the advertisers didn't like the amount of drugs/alcohol discussion that was on there, the forum never really recovered from that and is now a ghost place (a lot of folk went to Meta, which ofc put all the drugs discussion in a place which feds could find and loads of events got locked off over a period of 5-10 years).
That said, a lot of Fedi users are clued up enough to be able to switch instances and data, I suspect what will happen is Fedi will split between "normies" and the more alternative parts which will keep running (and/or Meta will give up on Threads integration when they find it doesn't make then any money)