For people that are not @actuallyadhd the common medication feels different that for those who are #actuallyADHD - non ADHDers feel like on Coke, very energetic and highly vibrant, similar to using Speed, while ADHDers tend to get calm and focused, able to concentrate at all.
Question [I haven't googled yet]: What is it with antidepressants - if people without a depression take those, do they feel LOTS happier than ever or something different?
I used to believe the same, but I was corrected recently. If ADHD medication works it is like a proof for actually having ADHD. But if one med doesn't work as expected it does not necessarily mean you don't have ADHD.
I was told that because I said that one aspect in motivation to try out meds is to know for super sure.
@rebekka_m@actuallyadhd@actuallyautistic Antidepressants can also work as dopamin antagonists, so they can do the opposite of make you feel happier.
I've read, that the effect shouldn't be that strong, even if you have ADHD, but when I took paroxetin, I felt like I couldn't enjoy anything anymore, which made me constantly crave for pleasure, without relief.
I took it for over a month and the effect took 3-4 month to fully wear off.
I wasn't depressed or anxious.
@rebekka_m@actuallyadhd@actuallyautistic Trimipramin on the other hand actually improves my mood, and makes me feel a bit "like a child on christmas eve", when I dose it low enough.
People react differently to drugs, so you can't really predict the effect they're going to have on any individual person.
And yeah, brain and neuro topics all are very diverse and individualistic - but I just wondered, and it already is paying off for me/my curiosity since all the different takes here :).
Tricyclics (I believe) are a an older class of anti-depressants. I haven't seen any studies on this, but SSRI/SNRIs are generally tried first. I think it is because there are less side effects.
@hauchvonstaub@actuallyadhd@actuallyautistic yeah, quick look at the wiki article, it says that the withdrawal symptoms of paroxetin are more/often than with other SSRIs. - Interesting effect with the reverse, until now I'd only heard of the "well known fact" that "all anti Ds do flatten your affects".
@rebekka_m@actuallyadhd@actuallyautistic I can't remember any withdrawal symptoms, just the regular effect of the drug not wearing off.
It did make me "emotionally numb", no fear, I didn't really care about anything, but I was also aggressive.(so it did flatten my affect)
It also suppressed empathy.
It would be long and complex to describe what paroxetine did, but it was generally unpleasant and I can understand, why one of the potential side effects is suicide.
@rebekka_m@actuallyadhd@actuallyautistic as far as I know there is still zero science to backup the idea that depression is related to a serotonin imbalance in the brain and there is little science that ssri actually effect serotonin levels in the medium to long term. As far as I know the pharma's still haven't tested for long term effects. They are now know to have addictive effects and serious problems for many when coming off them
@peterainbow@actuallyadhd@actuallyautistic thanks, will watch this in some days! And concerning your first response toot I found this very interesting paper from 2022 [unfortunately German]: "It is important to emphasize that it became clear early on that this mechanism is not specific in two ways." and so on and so on [deepl translation]. Thanks! https://link.springer.com/article/10.1007/s00739-023-00898-w
Can you site a source for addictive properties of SSRI'
s? There is a withdrawal side effects, but I'm not aware of anything supporting more than that.
There is (from memory) good evidence that SSRI/SNRI's have a positive impact with major depressive disorder - that doesn't mean the mechanism is via the Serotonin impact.
Remember that the serotonin in question is the synapse only - not easy to measure with out microsurgery, or without killing the patient.
The way I think of it is like an engine that you can't see any of the parts. You have to diagnose it based on the sound alone, and the only way of trying to fix it is to ass something to the fuel or hit the side of the engine with a hammer ..
@owenhollands@rebekka_m@actuallyadhd@actuallyautistic watch the bbc report and you'll get the idea. i understand that they are useful to people in crisis and am not advising people in that place what to do or think, but their long term use is just wrong and a cash cow to the pharma industry. their addictive and damaging nature ot some people prompted a heartfelt applology from senior psychs in the UK, daying they'd made the same mistake again as the previous generation of anti depressives
@rebekka_m
My experience has been that people without depression will get sick and feel weird on SSRIs (selective serotonin reuptake inhibitors), if anything. But a lot of people with depression have the same outcomes, too! And doctors do prescribe SSRIs off-label for other problems, even non-psychiatric problems. So I'm not sure if it's possible to get a definite answer on this one, but I hope to find out more from answers to your post.
Add comment