It works fine on a desktop with a single GPU mostly. Though I have had issues with multi monitor setup at work with xfce and xorg. I actually had a better experience with gnome and wayland, in terms of multi monitor support.
That said, all my own non work computers I use AMD/intel these days though. It just works now. I did have a bad experience years ago with an nvidia optimus laptop, where I couldn’t use the displayport without permanently enabling the nvidia GPU, killing battery life.