Tapentadol is primarily used for the management of moderate to severe pain. Tapentadol may be used for the treatment of chronic pain conditions such as neuropathic pain, musculoskeletal pain, and chronic back pain. It can be prescribed for managing pain following surgical procedures, providing relief during the postoperative recovery period. Tapentadol may be used as part of a pain management regimen for cancer patients experiencing moderate to severe pain that is not adequately controlled by other medications.