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JoBo, to news in For the jury in Trump's hush money trial, evidence of a criminal conspiracy comes in bits and pieces

The article is not arguing that it should have been any different. The sub-editor had a bad day and that’s OK.

JoBo, to news in US man has brain damage, mother says, after allegedly being pushed into lake

You can learn to swim in water that is shallow enough to stand in. And if being safe in the event of a pychopathic ‘prank’ is the primary concern, focus on learning how to tread water. Everything will seem easier once you know for sure that you can keep your head above water. Most people who are enjoying a pool or the sea are not actually swimming anywhere anyway.

JoBo, to news in Two newborn twins need a one-dose treatment that would save their lives: Zolgensma, a $2.1M drug. Insurance (also the mother's employer) cut coverage of the drug the day after they were born.

lol

JoBo, (edited ) to uk_politics in Rishi Sunak admits Tories may not win general election | ITV News

The fact Starmer won’t even think about joining the single market is stupid too.

Joining the single market would simplify border issues but it wouldn’t solve them… We’d have to join the Customs Union and the common VAT area as well to do that. SM-only is not completely pointless but there is a massive political risk attached because it doesn’t solve all the problems its advocates pretend it does.

There are only two ways to make Brexit work. One is to be an EU member in all but name (following all the rules but having a very limited role in making the rules). The other is a united Ireland (with a lot more expenditure on customs and warehousing in Britain).

The first is politically impossible, and also pointless. The second is up to the people of the island of Ireland and requires a British govt which is willing to invest in the real economy, rather than keeping most of us around to create the illusion of a real country instead of a tax haven based on a massive casino.

JoBo, to news in Two newborn twins need a one-dose treatment that would save their lives: Zolgensma, a $2.1M drug. Insurance (also the mother's employer) cut coverage of the drug the day after they were born.

Good grief. You don’t need to wave your hands so wildly, this is really fucking simple maths. Expenditure which is 21% of the total cannot possibly be the reason why USians pay 2-3 times more than everywhere else for drugs.

JoBo, to politics in ‘A better church is possible:’ Methodists celebrate as the church embraces the LGBTQ | CNN

They’ve been working on this for years, an opportunity to schism gracefully was offered in advance. In the UK, they’ve allowed individual congregations to decide what can happen in their church building(s), and individual clergy to opt out of officiating.

JoBo, to nostupidquestions in [Serious] Do you know of any processed snack foods with some vitamins?

Advising a parent to torture a child over food is piss poor advice to start with but when the parent has identified possible autism, you realise you know less than nothing and shut the fuck up.

JoBo, to news in Two newborn twins need a one-dose treatment that would save their lives: Zolgensma, a $2.1M drug. Insurance (also the mother's employer) cut coverage of the drug the day after they were born.

That’s a mind-numbingly obvious point which completely ignores the context, which is Pharma justifying their high prices based on the amount they spend on R&D.

The rest of the world gets drugs 2-3x cheaper than the US. Do you imagine they’re selling at a loss to everywhere else?

JoBo, to asklemmy in What did you get told as a child that you realised was a lie as you got older?

I don’t know which jurisdiction you’re in but, while it isn’t illegal in the UK, you’re absolutely right about it being a bad idea and you are correct about the reason. In the event of a crash, it could count against you (in the UK, at least).

JoBo, to news in Two newborn twins need a one-dose treatment that would save their lives: Zolgensma, a $2.1M drug. Insurance (also the mother's employer) cut coverage of the drug the day after they were born.

It doesn’t cost that much because the company are making a hefty profit, of course. And much more profit off it in the US as per usual, the NHS pays considerably less

The deal struck [in 2021] with Novartis Gene Therapies, secures the drug for NHS patients in England at a substantial confidential discount and paves the way for the National Institute for Health and Care Excellence (NICE) to publish draft guidance recommending treatment with Zolgensma.

The terms of the deal mean that some young children that currently fall outside the NICE recommendation criteria will also be eligible to be considered for treatment by a national multidisciplinary clinical team (MDT) made up of the country’s leading experts in the treatment of SMA.

This means as many as 80 babies and young children could potentially benefit from the life-changing gene therapy a year.

But profiteering aside, the number in the final paragraph is your answer. Up to 80 kids in the UK per year, so up to ~400 in the US, ~500 for the EU. It’s not a big market but the cost of drug development doesn’t get cheaper just because the number of cases is small, it gets more difficult and more costly. And there’s more than one drug company chasing the market.

None of that is a defence of Pharma. But it is inevitable under capitalism. Eat the rich etc etc.

JoBo, to news in Two newborn twins need a one-dose treatment that would save their lives: Zolgensma, a $2.1M drug. Insurance (also the mother's employer) cut coverage of the drug the day after they were born.

What percentage would be right?

Given that they’re using the cost of R&D to justify their prices? A lot more than 21%.

The rest of the world gets much lower prices. That’s not out of the goodness of their hearts or the generosity of their wallets, yaknow?

JoBo, to nostupidquestions in [Serious] Do you know of any processed snack foods with some vitamins?

So the fuck what?

JoBo, to nostupidquestions in [Serious] Do you know of any processed snack foods with some vitamins?

What did you think this bit meant?

(He’s likely on the spectrum.)

JoBo, to news in FTC fines Razer for every cent made selling bogus “N95 grade” RGB masks | Ars Technica

I don’t disagree with your overall argument but, if they’re fined 100% of revenue, that’s way less than zero profit (because they’ve still paid to make, distribute, and recall the things).

Fines should, of course, always be more than the profit made. 3x is a good number.

JoBo, to evs in BYD unveils luxurious Sea Lion 07 mid-size electric SUV interior poised to rival Tesla's Model Y

I don’t think we’d ever get real safety statistics about companies in China.

China cares a great deal about its exports, and the testing by ANCAP / NCAP / NHSTA is the same in those export markets. Their safety record is not something they can hide. BYD alone is outselling Tesla, so there will be a large volume of real world data coming along shortly. The NHSTA is too gutless to make Musk share the data but they won’t be so shy with Chinese brands.

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