“concentrations of IgG against SARS-CoV-2 spike and S1 in participants with long COVID were higher compared with vaccination-matched controls, suggesting persistent viral antigens. Even more strikingly, Peluso and colleagues observed T-cell activation up to 2·5 years after SARS-CoV-2 infection, especially in areas of the body such as the gut where SARS-CoV-2 RNA was identified, suggesting that tissue viral persistence could be associated with long-term immunological perturbations”
VVitchy