My main two guitars are a G&L s500 and a Godin nylon multiac. Amplification is a bit unconventional; I use a Roland KC 350 (or go DI if playing elsewhere), so I aim to get all the tone before the amp.
I play on the blues to rock spectrum with the G&L and go through a Boss OD-200 and an Award-Session Sessionmaster JD10. For folk and other stuff I use the Godin through a VG-88. There are other pedals.