Should I use QEMU/virt-manager or Virtualbox for a Windows virtualized instance?

I use Arch Linux, and some apps require me to use Windows. I have tried to get Wine working, but it’s just too much of a hassle. If the only goal of my virtualization setup is to run something like Adobe apps (I’m not doing any gaming on it), will Virtualbox or virt-manager be the quick and easy choice for me? I have tried...