"TRPM3 dysfunction in post-COVID-19 condition and ME/CFS participants suggests impairment in ion mobilization and consequently results in Ca 2+ signaling and cell homeostasis disturbance in both diseases. The NTX treatment restored TRPM3 ion channel activity in the post-COVID-19 condition group, facilitating Ca 2+ influx for intracellular signaling pathways."
@tomkindlon@mecfs@longcovid mmmm - interesting that the authors make claims for long covid: "This study showed that TRPM3 ion channel activity was restored in NK cells from post-COVID-19 condition patients after in vitro treatment with 200 μM NTX for 24 h.", but don't say the same for ME/CFS. Is there more going on in ME/CFS? However, it would be helpful to repeat the method in terms of developing a cllincal / physilogical /lab based test for ME/CFS
Add comment