It’s not really foreign many fruits have an even worse fructose/glucose ratio than HFCS.
The thing about fructose is that unlike glucose the body can’t burn it (pretty much) as-is, it first has to be processed by the liver, and that via turning it into fat. Evolutionarily that wasn’t an issue: Fruit appears in summer, exactly the time when you want to get fat to then have some storage for the winter, what the system isn’t made for is consuming the stuff all the time.
That is, HFCS in winter should be just as suspect to you as strawberries in winter.