Can say that my #Cloudflare#R2 block storage for #Mastodon is massively growing. A year ago it was stable at ~80-89Gb, but lately it's heading to 200Gb+ #Mastoadmin
The Chinese episode has also generated other issues. Several notes demonstrate that this was an experiment and not a therapeutic intervention (even He Jiankui called it a ‘clinical trial’). The babies were not at risk of being born with HIV, given that sperm washing had been used so that only non-infected genetic material was used. Further, even though one of the parents (or both) was infected, it did not mean the children were more prone to becoming infected. The risk of becoming infected by the parents’ virus was very low (Cowgill et al., 2008). In sum, there was no curative purpose, nor even the intention to prevent a pressing risk. Finally, the interventions were different for each twin. In one case, the two copies of CCR5 were modified, whereas in the other only one copy was modified. This meant that one twin could still become infected, although the evolution of the disease would probably be slower. The purpose of the scientific team was apparently to monitor the evolution of both babies and the differences in how they reacted to their different genetic modifications. This note also raised the issue of parents’ informed consent regarding human experimentation, which follows a much stricter regimen than consent for therapeutic procedures.
No HIV transmission occurred in 11,585 cycles of assisted reproduction using washed semen among 3,994 women (95% confidence interval [CI] = 0–0.0001). Among the subset of HIV-infected men without plasma viral suppression at the time of semen washing, no HIV seroconversions occurred among 1,023 women following 2,863 cycles of assisted reproduction using washed semen (95%CI= 0–0.0006). Studies that measured HIV transmission to infants reported no cases of vertical transmission (0/1,026, 95% CI= 0–0.0029). Overall, 56.3% (2,357/4,184, 95%CI=54.8%–57.8%) of couples achieved a clinical pregnancy using washed semen.
Rivian Hires New Marketing Leader as It Prepares to Unveil First Economy Line
Meta and Amazon veteran joins the EV startup, which will soon take reservations for its key R2 lineup
The first R2 is expected to go on sale in 2026 with a likely price range of $40,000 to $60,000, according to a Rivian spokeswoman, well under the cost of Rivian’s R1T truck.
WTF #BBCnews#PM From Iranian hostages... ragged cut to review of "Neighbours" and another ragged cut to Shakespeare's Shylock....? Like from #R4 to #R2 back to 4 and then #5live
Got rid of some relays (hard to pick which though, and #FOMO). But the load on my RPi became too much (regular OOMs or Mastodon unresponsive for a minute or so while #Sidekiq struggled) and my storage (#Cloudflare#R2) ballooned to ~190Gb… And 99.9% of the posts and media I would never even see.
Unfortunately allowing public access to media requires either managing DNS through CF or being limited to a managed domain which is rate-limited and not intended for production use.
Scientist who gene-edited babies is back in lab and ‘proud’ of past work despite jailing (www.theguardian.com)