andrewplested

@andrewplested@mstdn.science

Glutamate

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andrewplested, to random

PhD position in Marseille to work on neurons that sense CSF in the spine. Team of (CSHL ion channel course leader) Nicolas Wanaverbecq...

https://www.fens.org/careers/job-market/job/118125

andrewplested, to Neuroscience

Cryo-ET of the SC-CA1 hippocampal connection from Eric Gouaux group. Nice confirmation that GluA2 N-terminus is closer to the pre-synapse than to the post-synapse!

https://www.biorxiv.org/content/10.1101/2024.04.01.587595v1.full.pdf

andrewplested, to random

Me: 10.7Mb PDF, please reduce the file size.

Adobe Acrobat: OK, 11 Mb

#UploadLimit

andrewplested, to random

Greetings from the Space Science Journal.

I recently came across your article titled "Measurements of the timescale and conformational space of AMPA receptor desensitization".

I am writing to extend an invitation for you to submit your paper for publication in our journal.

andrewplested, to academia

Two big grant rejections within 10 minutes this morning, and this afternoon, teaching evaluations arrived.

What a day 😜

andrewplested, to random

Greetings Plested AJR,

I would sincerely appreciate it if you could spare 2 minutes of time.

Successfully, we have released enormous issues in our Annals of Advances in Chemistry (ISSN: 2576-3768). With the same spirit, we are moving ahead to accomplish this volume, and we need two articles to conclude the December issue.

andrewplested, to random

Hi,

Greetings from Journal of Women’s Health and Development (ISSN: 2644-2884)

PubMed Indexed and Impact Factor: .1.1

We are impressed with one of your publications entitled: The action of Con-ikot-ikot toxin on single AMPA-type glutamate receptors

We cordially invite you to submit same or similar article

andrewplested, to random

Your quest to explore new dimensions in your field that matches our journal's scope compels me to know more about your current research work. I can also connect you with our network of eminent researchers of your stream, along with recognizing your university.

Additionally, as I am Chief Author, I cordially invite you to send your future research articles/papers for publication in Global Journal of Science Frontier Research,

andrewplested, to random

Hello Manager,

Hope you are well!Glad to know that you are in the pharmaceutical industry.

andrewplested, (edited ) to berlin

My brilliant colleague Benjamin Judkewitz @benjulab tells us all about the smallest brain in the singing fish Danionella.

andrewplested, to random

Helge Ewers and Purba Kashyap developed an elegant way to trap proteins in the Golgi and uncage them with light. Sara Bertelli from our lab showed that it works well for BK , amongst other targets.

From: @bioRxiv_biophys
https://botsin.space/

andrewplested, to python

Trying to run my own software. 😂

I am "I followed my own instructions from GitHub and I can launch the app" years old.

lakens, to random
@lakens@mastodon.social avatar

It is often more worthwhile to read the best paper written in your field in 1972 than to read the latest paper everyone on social media is talking about.

andrewplested,

@lakens you could read BOTH

andrewplested, to random

"In December, we will issue student evaluations via email, which students do not check. You will probably get a response rate of 4 to 10 percent, which we’ll consider statistically valid for evaluating your teaching."

https://www.mcsweeneys.net/articles/congratulations-on-your-new-academic-position-of-assistant-professor-of-annual-reviews-merit-reviews-peer-reviews-student-evaluations-tenure-review-post-tenure-review-and-your-discipline

andrewplested, to Futurology

Pretty even-handed assessment of the success and failure of the EU-funded Human Brain Project, which is ending. Probably the most impressive thing is that, given its troubled inception, it produced some meaningful, if rather ad hoc, brain science.

https://www.nature.com/articles/d41586-023-02600-x

andrewplested,

@BorisBarbour @cian Excellent point. One might perhaps argue that the original centralised implementation of HBP was similar to Allen Brain Institute, it just went sour.

The ABI seems to be cheaper to run despite its much greater impact. $500m from Paul Allen, not including NIH support, but so far 20 years running time.

https://en.wikipedia.org/wiki/Allen_Institute_for_Brain_Science

neuralreckoning, to random
@neuralreckoning@neuromatch.social avatar

"It is part of the ERC’s core business to carefully select the best and most creative researchers from all fields in its grant competitions."

That started me wondering: is there any evidence that this is a valid approach?

For example, is there any evidence that giving funding to PIs to choose which postdocs to hire is more efficient than directly giving funding to postdocs and letting them choose who they want to be supervised by?

I'm glad that the ERC is making some small steps towards improving the way they evaluate research but I wonder if it's not missing a much bigger picture here. I've never seen any evidence one way or the other on this, but would be happy to be shown any if there is some.

https://erc.europa.eu/news-events/magazine-article/research-assessment-ScC-view

andrewplested,

@neuralreckoning I suppose you could compare to Marie Curie fellows. But the scale is different.

You might be asking the wrong question- it's not necessarily aiming to be efficient. They want to have a big impact. Do you meant that the outcomes could be better with more small awards?

One thing to note, there is almost the same amount of paperwork for a Marie Curie fellow and an grant. So in that sense, the ERC is more efficient (because the award is 10x).

Alice, to random
@Alice@beige.party avatar

Sometimes I convince myself that I’m not actually autistic since I’m not obsessed with things like trains or model cars, but then I spend an hour talking about the subtle differences between Helvetica and Arial and I’m like oh, okay, yep, there it is.

andrewplested,

@Alice @VoiceofDuum
Love Avenir.

andrewplested, to random

Nice review about synapses, why and how we have them.

Frontiers | Selective Advantages of Synapses in Evolution

https://www.frontiersin.org/articles/10.3389/fcell.2021.726563/full#B44

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