ddp

ddp, 1 month ago to mecfs

Public health briefing for New Zealand, but relevant in all countries.

"#LongCovid is associated with increased healthcare use, productivity loss, and workforce impacts, with implications for NZ workforces that experience high incidence of Covid-19“

"For the substantial sub-group meeting the criteria for #MECFS, research on this condition has shown that recovery after 2-3 years is uncommon with ME/CFS and that most people have significant long-term disability.”

https://www.phcc.org.nz/briefing/long-covid-aotearoa-nz-risk-assessment-and-preventive-action-urgently-needed

ddp, 2 months ago to ai

“Even healthcare workers are often shocked at how quickly they are dismissed and disbelieved once they become patients.”

“This disregard of patient experience and patient expertise severely limits medical knowledge. It results in delayed diagnoses, misdiagnoses, missing data, and incorrect data. AI is great at finding patterns in existing data. However, AI will not be able to solve this problem of missing and erroneous underlying data. "

#AI #LongCovid #MedicalBias

https://mastodon.social/

ddp, 3 months ago to random

Great work by the #TrinityCollege #Dublin team.

Evaluation of #LongCovid patients with cognitive dysfunction (“brain fog”) using dynamic contrast-enhanced #MRI .

Showing blood-brain barrier dysfunction, with #transcriptomics demonstrating related systemic inflammatory markers and immune dysregulation.

https://disabled.social/@tomkindlon/111977872800633267

ddp, 3 months ago to random

New Xe #MRI lung study into #LongCovid

"Low RBC/Mem in Cluster2 in the absence of airway or parenchymal abnormalities adds to the growing evidence of post-COVID microvascular abnormalities such as pulmonary capillary inflammation, vasoconstrictive remodeling or thrombosis that inhibit transfer of gas."

RBC/Mem ⬇️

“the ratio of 129Xe dissolved in RBCs to that in interstitial tissue and represents the efficiency of transfer of gas from the interstitium to capillary RBCs"

https://erj.ersjournals.com/content/early/2024/02/02/13993003.02301-2023

ddp, 5 months ago to random

New paper on exercise / exertion intolerance in #LongCovid from #Yale may be a key paper for 2023.

1️⃣Pulmonary & radial arterial catheters during upright exercise test

2️⃣Major abnormalities when conventional tests normal

3️⃣Shows problem is with the peripheral extraction of O2

4️⃣Not due to deconditioning (opposite shown with⬇️pEO2 and ⬆️peak cardiac output)

5️⃣Suggests impaired peripheral O2 extraction may be from capillaries➡️ muscle mitochondria not getting to capillaries.

https://openres.ersjournals.com/content/early/2023/12/07/23120541.00714-2023

ddp, 8 months ago to mecfs

Signed alongside many other patients and researchers, including @erictopol, who stated in one of this year’s most widely read medical review articles (1.04m):

"Of note, exercise is harmful for patients with #LongCOVID who have #MECFS or postexertional malaise and should not be used as a treatment; one study of people with long COVID noted that physical activity worsened the condition of 75% of patients, and less than 1% saw improvement.”

https://med-mastodon.com/@s4me/111005568964566137

erictopol, 9 months ago to random

An outgrowth of postural orthostatic tachycardia syndrome (POTS) from #LongCovid, photos below 0, 2 and 10 minutes after standing

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01461-7/fulltext

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