If you're not getting interviews then the issue probably has to do your resume. Maybe formatting. Maybe the contents or job history. Have you been out of work for a long time? Lack newer tools/knowledge? Too much job hopping?
If you are getting interviews then the resume and where you're applying is fine. Either you're probably lacking in soft skills, interview skills, or not impressing them. There could also be a mismatch between the salary you want and what they want to offer.