@fluffykittycat@danilo@irenes@bigzaphod Lower Decks establishes that Quark has had huge success since the DS9 days with his specially branded Quark 2000 replicator, which gives his cocktails an "extra zing."
Turns out Quark stole the tech from the Karemma, who arrest him in the "Hear All Trust Nothing" episode, so there's that.