mikemathia, to random
@mikemathia@ioc.exchange avatar

lukaso666, to random Polish
@lukaso666@chaos.social avatar

PLOSBiology, to Depression

deficiency underlies & disorders of motivation. Behavioral analysis & pharm manipulation in monkeys reveals distinct contributions of subtypes to reduced in terms of cost-benefit trade-offs https://plos.io/48kB11t

makkhorn, to random

REBOOSTED
HELP FOR LONG COVID

https://www.nytimes.com/2023/10/16/health/long-covid-serotonin.html?unlocked_article_code=1.Bk0.Fobf.Sn4C9mSf7KI3&smid=nytcore-ios-share&referringSource=articleShare

fu, to internet

Why does communicating via release the good chemicals so much more than e-mail? Why is the notification bell here much more interesting than the one in ?

CastlTrAstonDrs, to random
@CastlTrAstonDrs@med-mastodon.com avatar

Understanding Autocrine positive feedback of from activated proposed to be of widespread relevance in chronic such as , , , , chronic , , dysfunction, cerebral palsy, , .
https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1002/prp2.1136

CastlTrAstonDrs,
@CastlTrAstonDrs@med-mastodon.com avatar

Low levels might explain some symptoms, study proposes. Viral infection appears to influence blood concentrations of the chemical messenger—but the connection to cognitive impairment remains murky @ScienceMagazine.
https://www.science.org/content/article/low-serotonin-levels-might-explain-some-long-covid-symptoms-study-proposes

CastlTrAstonDrs,
@CastlTrAstonDrs@med-mastodon.com avatar

Nearly 1 in 5 people who have had in 🇺🇸 https://www.cdc.gov/nchs/pressroom/nchs_press_releases/2022/20220622.htm
Depletion of serotonin disrupts gut-to-brain communication, which can cause Neurological sx “brain fog” & impaired memory. As resulting in LC through a pathway that originates in the gut & leads to reduction. connects with gut & uses the neurotransmitter serotonin to communicate and regulate many biological & neurological functions

image/png

CastlTrAstonDrs,
@CastlTrAstonDrs@med-mastodon.com avatar

tissue damage, in some cases disrupt communication in the nervous system. https://www.science.org/doi/10.1126/science.abm8108 also interferes with the levels of several metabolites during the initial infection. Patients not only have lower levels of https://www.rcpjournals.org/content/clinmedicine/21/1/e63
but these imbalances can persist in those with
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111264/

image/png

CastlTrAstonDrs,
@CastlTrAstonDrs@med-mastodon.com avatar

These remnants of 🦠(a ) trigger the immune system to release virus fighting proteins ( ). The extended release of interferons caused chronic inflammation in lab mice & in LC patients https://www.nature.com/articles/s41590-021-01113-x Reduced levels due to in 🐁 disrupted their signaling & 🐁failed to distinguish new objects from familiar ones in tests.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332351/

CastlTrAstonDrs,
@CastlTrAstonDrs@med-mastodon.com avatar

🧪Can boosting levels treat ?
's might be useful in treating, or even preventing LC. When scientists gave Prozac to the lab 🐁 whose neurological symptoms mimicked LC because of viral infection—it restored their memory loss.
https://www.medrxiv.org/content/10.1101/2022.11.09.22282142v3

bespacific, to Cognition
@bespacific@newsie.social avatar

Full text study from Cell - https://www.cell.com/cell/fulltext/S0092-8674(23)01034-6
> is associated with reduced circulating levels
>Serotonin depletion is driven by viral -induced type I (IFNs)
>IFNs reduce serotonin through diminished# tryptophan uptake and
>Peripheral serotonin deficiency impairs via reduced signaling

morgan, to random

Scientists Offer a New Explanation for Long Covid https://www.nytimes.com/2023/10/16/health/long-covid-serotonin.html?smid=nytcore-android-share

Andy_European, to random
@Andy_European@mastodon.online avatar

Scientists Offer a New Explanation for

In some patients, remnants of the coronavirus in the gut may stifle production of , an important neurotransmitter, researchers suggest:

https://www.nytimes.com/2023/10/16/health/long-covid-serotonin.html?unlocked_article_code=-IinL8ytSea5giZzYrPLZbX43px36KeH9n1G68mJBW8wvT7emLI90pQGHujAA9YKsFJGmPkqzb9ESyaS_NCeMz9NOCUaUatEIH0ImVK5id0M9ghXcm38btOHdOqoUKzf7K2SKXAV3j5zhjj2kkVzwZkt6sVXWz6w704To_0ot6rttHMdwMD26YAYRmWeqFcHZPVkXmXObiFBPTiVb5Xk8nKgqwVoTvXSfBHsGKOS-zOHsA8KVHTz1pUis4iSxrUiTRwkvA_EDZJJgUsuXGePPIZ0fI3pbwdLBFr_-Q7KgUhJ4PW20YOwSCG2RQN4Dsag1-lPPSe4a4XffYfh1g&smid=nytcore-ios-share&referringSource=articleShare

🎁

jbzfn, to Depression
@jbzfn@mastodon.social avatar

:welp: @QuantaMagazine writes:
"They found no convincing evidence that lower levels of serotonin caused or were even associated with depression. People with depression didn’t reliably seem to have less serotonin activity than people without the disorder. Experiments in which researchers artificially lowered the serotonin levels of volunteers didn’t consistently cause depression."



https://www.quantamagazine.org/the-cause-of-depression-is-probably-not-what-you-think-20230126/

SuitedUpDev, to random
@SuitedUpDev@mastodon.online avatar

Should you be in (dire) need of some , I can highly recommend this video https://www.youtube.com/watch?v=PMV8V5XRPD0

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