@NicoleCRust@neuromatch.social avatar

NicoleCRust

@NicoleCRust@neuromatch.social

Professor (UPenn). Brain researcher. Author (nonfiction). Advocate for community based progress & collective intelligence.

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neuralreckoning, to random
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Three grant rejections in one week. Sigh.

NicoleCRust,
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@neuralreckoning
It’s rough when they pile up like that. Empathy and solidarity!

NicoleCRust, to random
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Many know about amyloid, the gene APP and its relationship to Alzheimer's. But how many know the backstory? It all began with a letter from Carol Jennings to John Hardy .... Wonderful tribute and retelling here in @thetransmitter.

Much gratitude, Carol Jennings. RIP.

https://www.thetransmitter.org/alzheimers-disease/carol-jennings-whose-familys-genetics-informed-amyloid-cascade-hypothesis-dies-at-70/

NicoleCRust,
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@barrygoldman1 @thetransmitter

Carol's family is among those with a type of rare genetic mutation that, if inherited, determines that an individual will develop Alzheimer's with near certainty. This is only true for ~1% of all individuals with Alzheimer's (more here: https://dian.wustl.edu/). For this group, there is very little question about the science. But tragically, we still don't have a cure for them.

But what I expect you are hinting at is also true: for the 99% of other individuals with Alzheimer's, what triggers it, and the role that amyloid plays in that, is a lot less clear. In some of those individuals, genetics leads to higher risk. For others, no genetic links have been found.

NicoleCRust, to random
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Summer reading recs?!

I’m looking to compile a big pile of IRL books for summer beach reading.

Big fan of scifi, specfic, murder mysteries. Strong female characters = bonus points. Can’t deal with darkness. Nothing high brow or tedious. Nonfiction lover but that list is already bursting at the seams.

I also love long series - 3 body problem, wheel of time, foundation … those waves all have good memories attached.

If that brings anything to mind, please send the rec!!

NicoleCRust,
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@adredish
Thanks! Not yet; I will.

NicoleCRust,
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@JosephMeyer
Looks excellent. Thank you!

NicoleCRust,
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@barrygoldman1
Looks fun. thanks!

NicoleCRust,
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@blainecross
Excellent. On it's way! Thank you.

NicoleCRust,
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@Scoobadood
I actually didn't know the Expanse was a great book series. Now I wish I would not have watched it first ... I'll still give it a try. thank you.

NicoleCRust,
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@theta_max
Excellent - added to the list. Thank you!

NicoleCRust,
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@D3Reo
@gregeganSF. Big fan here of Egan's books. I haven't read this set yet; thank you!

NicoleCRust,
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@adardis
A rare one from this list that I've read. I agree; great rec - thank you!

NicoleCRust,
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@jwc
Thanks!

NicoleCRust,
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@adardis
Didn't know these. Excellent!

NicoleCRust,
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@csgordon
Looks really great. On it's way. Thanks!

NicoleCRust,
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@dcm
That's a rare combo. Thank you! I'll check it out.

NicoleCRust,
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@kimhoar
thanks!

NicoleCRust,
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@cmaclell @dcm
Sounds delightful; thank you.

NicoleCRust,
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@zeh
Super - thank you!

NicoleCRust,
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@axoaxonic
Oh wow - I'll definitely check those out. Thanks!

NicoleCRust,
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@olena
Thank you!

davidtoddmccarty, to random
@davidtoddmccarty@me.dm avatar

FOLLOW ME: You might not like everything I have to say but I’ll make you think. Of course, that might include thinking I’m an idiot. I write about politics, culture, writing, and quite a lot of random shit, but it’s almost always my original thoughts and insights. Funny, apoplectic, or morose. But honest.

Maybe I could ask you to boost so I may continue my effort to conquer the world.

NicoleCRust,
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@davidtoddmccarty
Well said. And accurate. I don’t always agree with you, but I appreciate your thoughtfulness and authenticity. And the experience of having something concrete to agree/disagree with. Cheers and gratitude to that!

elduvelle_neuro, to random
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The last ’ll be building here in the US!
(I’m leaving my current postdoc in 6 weeks to go on holidays and then maybe another postdoc in Glasgow!)

NicoleCRust,
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@elduvelle_neuro
Happy holidays! And best wishes. Keep us posted!!

NicoleCRust, to random
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Sometimes I think that maybe (just maybe) I write well ...

Then I encounter someone who writes REALLY well (sometimes a revising my own text).

Sigh ... focusing on the delta can be hard. But inspiring and motivating too.

The deeper I get into it, the more I realize: writing (compelling nonfiction) is an art form.

NicoleCRust,
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@knutson_brain
Thank you!

NicoleCRust,
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@dsmith
Ah, shucks. Thanks!!

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