bespacific, to random
@bespacific@newsie.social avatar

Eighty percent of patients with are female. These diseases are one of the top 10 leading causes of death for women under 65, and cases are increasing annually worldwide. There is evidence suggesting that it's females’ double complement of X that puts them at such heightened risk for autoimmune diseases. Female cells have two X chromosomes, whereas males have one X chromosome and one Y chromosome (at least in mammals). https://arstechnica.com/science/2024/02/female-propensity-for-autoimmune-diseases-tied-to-x-chromosome-inactivation/

ThunderHoneySnow, to Futurology

Lupus trigger discovered

Researchers were able to trace a form of the autoimmune disease lupus back to a single mutation

https://www.mpg.de/21374791/lupus-trigger

terrygrundy, to random
@terrygrundy@mas.to avatar

“These results astounded us all. They provide a huge leap forward in our understanding of the evolution of MS and other autoimmune diseases. Showing how the lifestyles of our ancestors impacted modern disease risk just highlights how much we are the recipients of ancient immune systems in a modern world.”

https://www.cam.ac.uk/stories/disease-spread-mapped-using-ancient-DNA?utm_medium=social&utm_source=linkedin

albertcardona, to random
@albertcardona@mathstodon.xyz avatar

An inverse vaccine to combat autoimmune diseases. How did I miss this giant piece of news!

"Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses", Tremain et al. 2023 https://www.nature.com/articles/s41551-023-01086-2

Surely there are already clinical trials.

Sure beats the crude cyclophosphamide approach to killing antibody-producing B cells that are undergoing mitosis – a protocol I applied back in my PhD times to select for monoclonal antibodies against specific tissues.

appassionato, to books
@appassionato@mastodon.social avatar

The Invisible Kingdom: Reimagining Chronic Illness

A landmark exploration of one of the most consequential and mysterious issues of our time: the rise of chronic illness and autoimmune diseases.

@bookstodon



rolandelli, to random
@rolandelli@sfba.social avatar

There is a second research study showing possible autoimmune curative treatment that avoids wide spread immuno suppression in patients.

The previous one was regarding a "reverse vaccine". Are there any rheumatologists or researchers on here that can explain these findings in layperson terms?

Are they both targeting T cells?

https://www.nature.com/articles/s41591-023-02613-z

CastlTrAstonDrs, to random
@CastlTrAstonDrs@med-mastodon.com avatar

@jama_current are still long & winding road to recovery. The data suggest that & connective tissue disorders may manifest as with the potential long-term health ramifications associated with .

Risks of Incident Autoimmune and Autoinflammatory Disease Outcomes in the COVID-19 Cohort Compared With the Control Cohort

CastlTrAstonDrs,
@CastlTrAstonDrs@med-mastodon.com avatar

Possible associations of with have been suggested, because appears to perturb self-tolerance & trigger autoimmune reactions via cross-reactivity that may lead to the development of autoimmune diseases, Vaccinated at lower risk
Relative to controls, significantly higher risks of (aHR, 1.12), (aHR, 1.74), antineutrophil cytoplasmic antibody–associated vasculitis (aHR, 2.76), (aHR, 1.68), (aHR, 1.59).

keithb7862, to random

MUST READ Okay, it's here, what I've been waiting for . . . the cure for all auto-immune disorders. When I first learned scientists in 2018 discovered a bacterial gut biom connection for Type I Diabetes, I sensed this was possibly the root cause of nearly ALL auto-immune conditions. BOOM! Here we go!! Just read this well-written post. This is very, very exciting indeed!!!!!! https://www.dailykos.com/stories/2023/9/15/2193137/--Inverse-vaccines-could-be-the-beginning-of-the-end-for-autoimmune-disorders

CastlTrAstonDrs, to random
@CastlTrAstonDrs@med-mastodon.com avatar
samhainnight, to Health
@samhainnight@mstdn.social avatar

Ever wonder why you have Crohn's Disease? It could be because your ancestors survived the Bubonic Plague in the 14th Century.

Gene associated with Black Death survivors linked to autoimmune disorders.

https://www.theguardian.com/society/2022/oct/19/gene-black-death-survivors-linked-autoimmune-diseases

  • All
  • Subscribed
  • Moderated
  • Favorites
  • JUstTest
  • ngwrru68w68
  • everett
  • InstantRegret
  • magazineikmin
  • thenastyranch
  • rosin
  • GTA5RPClips
  • Durango
  • Youngstown
  • slotface
  • khanakhh
  • kavyap
  • DreamBathrooms
  • provamag3
  • tacticalgear
  • osvaldo12
  • tester
  • cubers
  • cisconetworking
  • mdbf
  • ethstaker
  • modclub
  • Leos
  • anitta
  • normalnudes
  • megavids
  • lostlight
  • All magazines