"Many weak and few strong links" seems to be a common pattern in many #EcologicalNetworks. We show that this skewness in interaction strengths can enable stabilising effects of network structure. It should hence receive more attention in #TheoreticalEcology and #EcologicalModelling, especially in studies based on random matrices!
(Btw, just in case you are looking for guest speakers, I highly recommend the first author, Franziska Koch! 😉)
How interesting. In #neuroscience, the brain #connectome – the pattern of synaptic connections among neurons – is also organized with many weak and few strong links.
Brenner, without skipping a beat, stated this served his purposes just fine: to study variability in synaptic connectivity among otherwise isogenic animals – and found lots, enough to state that genetic determinism w.r.t. neural circuit configuration as understood at the time was largely hogwash.
I am looking forward to discussing our work on the #Drosophila optic lobe #connectome. Find me at #SfN23 today from 1pm to 5pm (poster 308.01 at board WW77).
Really excited to share the lab's first Drosophila paper and it's a big one. Check out our preprint https://shorturl.at/gqrvO where we present the complete neural connectome of an animal circadian clock . 🧵 (1/8) #Drosophila#neuroscience#connectome
Mubarak Syed kicking off the #pbsscb grounding us in the land and the history and the rich diversity of the Pueblo of Sandia. https://www.pueblobrainscience.org absolutely tremendous outreach efforts bringing in and supporting tomorrow’s scientists.
Jim Truman leads with #metamorphosis of the #Drosophila mushroom body (a locus of memory). He's walking us through a most beautiful piece of work. Special shout-out to the foresight it took to begin this work before there was a #connectome available so as to inform ongoing work.
tl;dr the molecular events that shape larval development can fade, allowing trans-differentiation of neurons (a shift from one brain area to another).
The #HHMIJanelia FlyEM MANC #connectome is now available on NeuronBridge.janelia.org. #Drosophila#Neuroscience researchers can use this tool to match the MANC electron #microscopy (EM) data against light microscopy (LM) data, like that from the Janelia FlyLight project. A user can interactively examine matches right in the browser by clicking the "View in 3D" button. Interactive views are sharable, too... (1/3)
Open science project OpenWorm simulates the roundworm Caenorhabditis elegans at the cellular level.
A deep, principled understanding of the biology of this organism remains elusive.
The long-term goal is to model all 959 cells of C. elegans. This bottom up simulation is pursued by the OpenWorm community.
Congrats to co-first authors Michael Winding and Benjamin Pedigo, and to all our lab members and collaborators who made this work possible over the years. A journey that started over 10 years ago–and yet this is but a new beginning. So much more to come.