#PASC is the American acronym - other health organizations in other countries use different acronyms.
Every acronym is associated with different criteria - different lengths of time, different combinations of symptoms, different criteria for new-onset symptoms.
#LongCovid unifies the patient experience under one name, so we literally have a common name as well as a technical term.
@BlackAzizAnansi
best I can suss these people think the following:
-it feels like a cold, must be a cold
-the more I expose myself sans NPIs the more immunity will build & eventually there will be zero symptoms
-everybody, including people older & more vulnerable than me seem fine, so it must be fine
-I’m vaccinated so that’s why it’s not severe & it will protect me from this so-called #longCovid
-I’m healthier than those that get #PASC
-I’m special
🙄 #christmas2023#misanthrope🎄🎄☃️😷😷
A Bad Blood Vessel – Neuroinflammation Connection Shows Up in Long COVID.
“To our knowledge, ours is the first study to provide direct evidence that processes related to neuroinflammation and vascular dysfunction are directly related in post-acute sequelae of COVID-19 (PASC) long COVID.”
“#LongCOVID is associated with reduced measures of exercise performance and skeletal muscle oxidative capacity in the absence of evidence of microvascular dysfunction, suggesting mitochondrial pathology. There was evidence of attendant ANS dysregulation in a significant proportion”
Microvascular Capillary and Precapillary Cardiovascular Disturbances Strongly Interact to Severely Affect Tissue Perfusion and Mitochondrial Function in ME/CFS Evolving from the #PostCOVID-19 Syndrome
2/
A hypothesis article describing a vicious cycle of circulatory disturbances leading to "a particular kind of perfusion disturbance - capillary ischemia-reperfusion - which has a high potential of causing mitochondrial dysfunction by inducing sodium- & calcium-overload in skeletal muscles” #mecfs
“fatigue was most common symptom (35.4%) which represents the most debilitating #longCOVID symptom, & the first reason patients seek for medical assistance…concerning as,in Africa,it has the potential to lead to important impairment in productivity & further loss of economic agency”
“we have demonstrated that there were no statistically significant differences in the retinal microvasculature of patients with #postCOVID19 syndrome compared to healthy cohorts. Furthermore, no significant structural differences were observed in the macular retinal nerve fibre layer (RNFL) & ganglion cell layer (GCL) of the study participants”
“Patients showed cognitive slowing indicated by longer reaction times compared to control participants (r = 0.51, p < 0.001) in a simple-response tonic alertness task & in all more complex tasks requiring speeded performance”
"High risk" has been twisted to focus exclusively on the potential for "severe" acute COVID (aka hospitalization for), ICU stays, and mortality, entirely omitting the high risk of morbidity conferred by reinfection after reinfection: organ and other compounding systemic damage, newly-developed cancer / autoimmune disease / chronic illness, and any other sequelae that slip through the diagnostic cracks.
Long Covid’s fatigue and PEM appear to be similar or identical to other post-infectious disease syndromes such as ME/CFS. The problem is that medical researchers are specialized by body system and there are very few people who even seem to know about post-infectious diseases syndromes, let alone study it. You would think that ID specialists would, but they seem to be focused on immediate issues associated with acute infections, and not about the long-term multi-system deficits that those infections can result in for many people. The result is that those suffering from these syndromes are either assumed to have mental health issues (we often do, but as a consequence not as a precipitating factor) or painted as malingerers.
#covidheart Spectrum of Pathophysiology of Cardiovascular Involvement Due to #COVID19 & #PASC-#CVS. Chronic inflammatory🫀 involvement affects a much broader segment of previously well people who may had only an acute #SARSCoV2 infection . The symptoms commonly develop after a delay of weeks or months after a period of relative recovery from the acute phase. Symptoms related to the 🫀 system : exertional dyspnoea, exercise intolerance, chest tightness, pulling or burning chest pain & palpitations
Study: Regardless of variant, half of long-COVID patients fail to improve after 18 months
"At 1.5 year after infection, patients had no clinically meaningful decline in severity of long COVID, and 57% (245/429) of patients failed to improve 1.5 years after infection, with no differences between variants," the authors wrote.
> During the 12-month follow-up period, 2.8% of the individuals with PCC vs 1.2% of the individuals without #COVID19 died, implying an excess death rate of 16.4 per 1000 individuals.
"7) "There is evidence that ME/CFS and #PASC share a common symptomatology and, possibly, similar aetiology [26]." Physicians and others who are treating patients with PASC need to made aware of the possible risks and harms that may ensue from the use of GET with or without CBT."