thor, (edited ) to random
@thor@berserker.town avatar

https://blog.addgene.org/crispr-101-off-target-effects

Nobody's been writing in the news about all the problems that have been discovered with . The reason you aren't hearing about CRISPR anymore is because of that.

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

STAT+: CRISPR edits fail to cure HIV patients in early test

https://www.statnews.com/2024/05/10/hiv-excision-crispr-trial/?utm_campaign=rss

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

STAT+: Pharmalittle: We're reading about MDMA for PTSD, a CRISPR treatment for blindness, and more

#crispr #fda

https://www.statnews.com/pharmalot/2024/05/07/mdma-ptsd-lykos-pfizer-zydus-abortion-mifepristone-fda-viagra-rnd/?utm_campaign=rss

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

The one huge obstacle standing in the way of progress on gene-editing medicine

https://www.vox.com/the-highlight/24105096/crispr-gene-editing-theory-dna-diversity

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

STAT+: Moderna ends collaboration with CRISPR company Metagenomi, parts ways with gene editing chief

https://www.statnews.com/2024/05/01/moderna-ends-metagenomi-collaboration-gene-editing/?utm_campaign=rss

thejapantimes, to worldnews
@thejapantimes@mastodon.social avatar

New AI technology is generating blueprints for microscopic biological mechanisms that can edit your DNA, pointing to a future when scientists can battle illness and diseases with even greater precision and speed than they can today. https://www.japantimes.co.jp/news/2024/04/25/world/science-health/generative-ai-crispr/

jackhutton, to ai
@jackhutton@mstdn.social avatar

[NYTimes]: Generative A.I. Arrives in the Gene Editing World of CRISPR

Much as ChatGPT generates poetry, a new A.I. system devises blueprints for microscopic mechanisms that can edit your DNA. By Cade Metz

https://www.nytimes.com/2024/04/22/technology/generative-ai-gene-editing-crispr.html?smid=nytcore-ios-share&referringSource=articleShare&sgrp=c-cb

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

STAT+: In a scientific first, researchers use CRISPR base editing to treat liver disease in fetal monkeys

https://www.statnews.com/2024/04/22/crispr-base-editing-in-womb-fetal-monkeys-liver-disease/?utm_campaign=rss

mattotcha, to Health
@mattotcha@mastodon.social avatar

Scientists say they can cut HIV out of cells
https://www.bbc.com/news/health-68609297 —editing

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

Getting CRISPR treatments to patients remains a major challenge. Could lab-developed tests help?

https://www.statnews.com/2024/03/21/crispr-gene-editing-personalized-medicine-batten-disease/?utm_campaign=rss

universalhub, to Biotechnology
@universalhub@mastodon.online avatar

Mass. General reports first ever transplant of a genetically modified pig kidney into a person


https://www.universalhub.com/2024/mass-general-reports-first-ever-transplant

cbarbermd, to Biotechnology
@cbarbermd@med-mastodon.com avatar

Using CRISPR gene-editing technology, scientists have successfully snipped out HIV from infected cells. Much more work needs to be done before this could possibly be used in people, but it’s a start...

https://www.bbc.com/news/health-68609297

tylerknowsnothing, to science
@tylerknowsnothing@mastodon.social avatar

While there are numerous caveats, there are now two gene editing therapies available for people with Sickle Cell Disease, and early therapies have been very successful. It's nowhere near cheap at over $2M for one and over $3M for the other, but it's a start I suppose. Only the 1% can afford such therapy for now, but if sanity ever returns to society, I would hope that empathy will eventually win out over profits in the end. https://youtu.be/uHWD8RSw4As

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

STAT+: Vertex hits speed bump in getting CRISPR sickle cell therapy covered in U.K.

https://www.statnews.com/2024/03/14/vertex-uk-casgevy-nice/?utm_campaign=rss

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar
snailman, to snails
@snailman@ecoevo.social avatar

CRISPR-Cas9 gene editing in apple 🍎 snails 🐌 - oh wow! By the new Accorsi lab https://www.accorsilab.com/ https://www.biorxiv.org/content/10.1101/2024.01.26.577494v1

flowolf, to Biotechnology German
@flowolf@graz.social avatar

Wirklich gutes ECO Spezial zu .

Erklärt schön was tut, und warum es eigentlich keinen Grund für die Angst gibt, die viele vor 'Gentechnik' haben. Natürliche sind ein Eingriff, der schon seit Jahrtausdenden durch den Menschen passiert.

https://tvthek.orf.at/profile/Eco/11523082/Eco-Spezial-Gentechnik-Ja-natuerlich-Landwirtschaft-zwischen-Wissenschaft-und-Marketing-vom-25-01-2024/14210700

eLife, to Biotechnology
@eLife@fediscience.org avatar

This recently revised builds on a method of genetic control for insect populations called pgSIT that uses -Cas9 to cause male sterility and female inviability in mosquito populations. https://elifesciences.org/reviewed-preprints/90199?utm_source=mastodon&utm_medium=social&utm_campaign=organic

JostMaurin, to Biotechnology German
@JostMaurin@dju.social avatar

Der Umweltausschuss des EU-Parlaments spricht sich gegen die Kennzeichnung von mit neuen -Methoden wie erzeugten Lebensmitteln aus. -Bauern, Umweltschützer und Grüne hoffen jetzt auf das Plenum https://taz.de/!5984645/

KnowableMag, to Biotechnology
@KnowableMag@mstdn.science avatar

With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot going on in the genome editing field. Here’s our primer. https://knowablemagazine.org/content/article/living-world/2024/crispr-gene-editing-therapy-systems-eukaryotic-cells?utm_source=mastodon&utm_medium=post&utm_campaign=originals

kofanchen, to Bulgaria
@kofanchen@drosophila.social avatar

Was not aware debate at , only to notice two opposing campaigns with some heavy weight geneticists backing one side or another

Apparent the vote for MEP is next Wednesday

Wondering thoughts on this on Mastodon?

See each camps in the thread👇

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar

STAT+: CRISPR-edited pig liver from eGenesis passes first test in brain-dead human, researchers say

https://www.statnews.com/2024/01/18/egenesis-crispr-pig-liver-tested-in-brain-dead-patient/?utm_campaign=rss

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar
auscandoc, to Biotechnology
@auscandoc@med-mastodon.com avatar

I received the new gene-editing drug for sickle cell disease. It changed my life. | MIT Technology Review https://www.technologyreview.com/2023/12/04/1084209/vertex-exacel-approval-gene-editing-sickle-cell-disease-patient/ “I’d lived with my whole life—experiencing chronic pain, organ damage, and hopelessness. To me, this opportunity meant finally taking control of my life and having the opportunity to be a present father.

The drug I received, called , could soon become the first -based treatment to win approval from the US Food and Drug Administration,”

br00t4c, to Biotechnology
@br00t4c@mastodon.social avatar
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