Yes, I can live without youtube I survived the 1980s and 1990s - I'm not saying my life is or was "meaningful" though - that'll be discernable if the maggots enjoy their dinner whenever the time comes.
I also think there were at least a few generations of humans before that, some of whom may think they led at least slightly meaningful lives.
I don't think youtube makes anyone's life more or less "meaningful", it's just a way to pass the time - but that's just my opinion on carbon-shuffling in general. If you accept peoples own objectives instead of mine, then youtube might help them learn stuff - but even then I'd look to measure the content of their consequent actions, much more than learning in abstract. They've still got to put their new knowledge together with skills , practice and the real world circumstances to before anyting "meaningful" happens - and that's due as much to their hard work as much as to their teacher.
But I do prefer to watch a few people's videos on there as entertainment, only a few of them post on that p2p thing "lbry" or whatever so i dont use that. I will continue to watch youtube videos given the choice, and not having somethign better to do, until those people move their videos to somewhere else.
I've recently been finding out that freetube client removes much of the front end unpleasantness.