@cstross But why? Users have to take Ozempic their whole life! They are buying fast food/drinks like before but now without weight increase. This doesn’t make sense to me, if anything those brands should be thriving even more! It’s not like Ozempic does deincentivize you to eat junk food.
Edit: According to this toot it actually does?!
@cstross Doesn't it just mean that people can have all the tobacco, candy, and alcohol they want, and then just have a shot of Ozempic for the consequences? You'd think they'd be thrilled.
@genecowan@cstross No, actually, because these sorts of drugs literally make you stop wanting those things! Ozempic and the like don’t get rid of the consequences; they alter the way the reward pathways in the brain operate, changing behavior. It’s fascinating, amazing, and terrifying all at once.
@gregly@genecowan Yes, I'm seeing it from inside. I pretty much gave up drinking alcohol at home: these days I'm purely a social drinker, and as we've still got COVID doing the rounds I don't do pub sessions nearly as often as I used to. (Used to be 2-3 nights a week; now it's 2-3 times a month.)
@zdl The XBox game controller was about the only sensible design decision they made on the Titan—they're cheap, robust, easily replaced, and everyone under 40 knows how to use it. (They're used for military drones as well these days.)
@zdl XBoX controllers are designed for controlling a six-axes-of-freedom flying viewpoint with dakka-dakka and missile launchers in a game. They're mass produced for a fraction the price of the actual Mil-STD real thing. And they've been around long enough that people who are actually fighting wars (eg. Ukraine, Armenia) are using them in new weapons systems because not only are they cheap, the soldiers require less training.
@Jennie They're all over the news? Available on the NHS in the UK for type II diabetes, available to some patients for weight loss (restrictions apply due to price and side-effects—it's not for casual use). I've been on Rybelsus (an oral form) for diabetes for nearly two years and have lost 15% of my body weight and my blood sugar is now firmly under control. But the side-effects are very Not Fun At All. (Ever wondered what it's like to want to throw up for three whole months, non-stop?)
@cstross if so, I expect fascist-era food & drug administrations will quickly find Reasons Ozempic is much deadlier than, say, radium or arsenic in food, so must be Banned.
@oddhack Won't happen: it's the new wonder drug for type-II diabetes right now, weight loss and loss of interest in addictive behaviour are among the side-effects. (Along with ghastly indigestion and nausea—ask me how I know😖)
@ivor Semaglutide first got a product license in the USA in 2017; it'll be out of patent by 2035 (although some formulations will doubtless stay expensive). The way demand and manufacturing are scaling up it's going to get a lot cheaper (like H2 antagonists for stomach ulcers in the late 70s/early 80s). There are already other GLP-1 agonists on the market, notably tirzepatide and lirglutide, and other drugs affecting GIP and glucagon receptors.
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