@MolemanPeter@neuromatch.social
@MolemanPeter@neuromatch.social avatar

MolemanPeter

@MolemanPeter@neuromatch.social

Hersenvorser, Brain explorer
R. Feynman: I’m an explorer? I get curious about everything, and I want to investigate all kinds of stuff.
I have been a psychopharmacologist and professor of Biological Aspects of Psychopathology until my retirement in 2013. Now I study the brain and write short assays, see my website. I am also writing a book (provisional title: Our Brain, the Body of the Mind). I use mastodon to keep up with developments in the field. Please post your publications with #neuroscience. I endorse Tootfinder which is an Opt-in global Mastodon full text search.

This profile is from a federated server and may be incomplete. Browse more on the original instance.

elduvelle, (edited ) to random
@elduvelle@neuromatch.social avatar

#Zotero still asking $60 for 1 year of 6Gb… 😭 @zotero I love you all but it’s 2024 now, maybe you could either reduce the price or increase what we get for it?
#ReferenceManager

Edit: not even 60… just SIX

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@elduvelle @zotero I left years ago because is much better and I have never paid a penny.... I always store data on my own laptop.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar
davidho, to random
@davidho@mastodon.world avatar

Behold the longest tunnel specifically built for biking and walking.

Timelapse through a 3 km tunnel lit by different color lights in different sections

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@davidho Where is this?

MolemanPeter, to random
@MolemanPeter@neuromatch.social avatar

Across every aspect of being a self, we perceive ourselves as stable over time because we perceive ourselves in order to control ourselves, not in order to know ourselves.

Seth, Anil. Being You: A New Science of Consciousness (The Sunday Times Bestseller) (p. 222). Faber & Faber. Kindle-editie.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@jonny I agree. Would you agree to the following: every person percieves himself as stable, but nobody really is stable (according to Seth): changing in time, in different situations etc. In queer people there is a more obvious discrepancy (or more at the surface?): between embodied self (experiences that relate directly to the body) and perspectival self (= subjective perception).

"This perspectival self is nowhere better illustrated than in the Austrian physicist Ernst Mach’s self-portrait, also known as ‘View from the Left Eye’."

Seth, Anil. Being You: A New Science of Consciousness (The Sunday Times Bestseller) (p. 179). Faber & Faber. Kindle-editie.

NicoleCRust, to random
@NicoleCRust@neuromatch.social avatar

Fascinating first person account by a psychologist who faked data

The scientist: Diederik Stapel. A Dutch social psychologist. He wrote a book explaining the context and how one thing led to another until he was caught. Nick Brown translated it into English. Freely available here:

http://nick.brown.free.fr/stapel

Page 101:

I also became increasingly skilled in the use of techniques that could put a healthy-
looking shine on otherwise mediocre results. If I didn’t get the effect I wanted across all the
different measures I’d used or the questions I’d asked, I would use the ones that did show
that effect. If an effect was present in an experiment, but not strongly enough to be tapped
by all of the types of measurements I’d used, I would make it stronger by combining the measures where the effect seemed to be only partly working. ...

Page 102:

After years of balancing on the outer limits, the gray became darker and darker until
it was black, and I fell off the edge into the abyss. I’d been having trouble with my
experiments for some time. Even with my various “gray” methods for “improving” the data,
I wasn’t able to get the results the way I wanted them. I couldn’t resist the temptation to go wanted it so badly. I wanted to belong, to be part of the action, to score. I really, really wanted to be really, really good. I wanted to be published in the best journals
and speak in the largest room at conferences. I wanted people to hang on my every word
as I headed for coffee or lunch after delivering a lecture. I felt very alone.

p103

I was alone in my tastefully furnished office at the University of Groningen. I’d taken
extra care when closing the door, and made my desk extra tidy. Everything had to be neat
and orderly. No mess. I opened the computer file with the data that I had entered and
changed an unexpected 2 into a 4; then, a little further along, I changed a 3 into a 5. It
didn’t feel right. I looked around me, nervously. The data danced in front of my eyes.
When the results are just not quite what you’d so badly hoped for; when you know that that
hope is based on a thorough analysis of the literature; when this is your third experiment
on this topic and the first two worked great; when you know that there are other people
doing similar research elsewhere who are getting good results; then, surely, you’re entitled
to adjust the results just a little?

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @PessoaBrain Which part of his text do you trust and which do you think is made up?

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@emma_cogdev @NicoleCRust I followed the case here in Holland when it was unfolding. It lookes like Diederik Stapel has never cared a lot about truth or the consequences of his behavior for other people, like his (junior) collaborators. Perhaps the publish or perish culture enabled this, but Stapel is not one of the normal scientists going astray. One of the (3) dutch Committees that investigated the fraud states:
"In discussions at lab meetings, critical questions in the direction of data collection were not appreciated. In this regard, Mr. Stapel was always clear in his communication when one should stop asking questions. Several doctoral students also indicated in interviews with the Levelt Committee that Mr. Stapel abused his position of power to silence them. To one research master's student, who found suspicious patterns in the data, Mr. Stapel indicated, 'If you want to be hired here, you have to show that you can finish something and just write down the results.'"
Translated with DeepL.com (free version)
@PessoaBrain @lf_araujo @jonny @skarthik @Herman @jonobie @dumoulin @PeterLG

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

The reviewers (Borsboom and Wagenmakers ) describe the final chapter of the book as "unexpectedly beautiful" but consider that many of its lines are "copied" from the works of writers Raymond Carver and James Joyce, without due acknowledgement.[37] Borsboom and Wagenmakers reviewed the Dutch language edition; the English translation of Stapel's Ontsporing by Nicholas J. L. Brown includes a note regarding "Chapter 10 ½":[38]
which acknowledges the sources Carver and Joyce.
@emma_cogdev @NicoleCRust @PessoaBrain @lf_araujo @jonny @skarthik @Herman @jonobie @dumoulin @PeterLG

glynmoody, to random
@glynmoody@mastodon.social avatar

Air #pollution could be significant cause of #dementia – even for those not predisposed - https://www.theguardian.com/environment/2024/feb/21/air-pollution-could-be-significant-cause-of-dementia-even-for-those-not-predisposed?CMP=twt_a-environment_b-gdneco "People in areas of high PM2.5 concentrations had higher amounts of amyloid plaques in brain"

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@glynmoody It is very easy to point out the plethora of bias that would (or will) invalidate the conclusion of a causal relationship between dementia and air pollution in this investigation. Right @lakens
https://www.theguardian.com/environment/2024/feb/21/air-pollution-could-be-significant-cause-of-dementia-even-for-those-not-predisposed

brembs, to Neuroscience
@brembs@mastodon.social avatar
MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @brembs @albertcardona @PessoaBrain Has this to do with efference copies/corollary discharge?

jonny, to random
@jonny@neuromatch.social avatar
MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@jonny That's called experimental statistics.

NicoleCRust, to random
@NicoleCRust@neuromatch.social avatar

Do psychologists "measure"?

Weird question, right?

"Measurements of attributes such as emotions, well-being, or intelligence are widely used for various purposes in society, but it remains a matter of discussion whether psychological measurement is analogous to measurement in the natural sciences, and to what extent it qualifies as measurement at all.'
https://doi.org/10.1080/09515089.2023.2300693
Edit: author is here! @mieronen

My initial take: what?! This seems silly. But I'm starting to warm up to it. It's about causality. Consider: "insomnia causes fatigue"; no one disputes it. But there's not a physical thing in the world called insomnia that causes a physical thing in the world, fatigue billiard-ball-style. Rather, the physical causal chain happens by way of a lack of sleep causing the brain state that leads to the mind state of fatigue (in other words, that word "cause" is doing some heavy lifting in that phrase). The question is: can you meaningfully talk about causality when you have abstracted away from physical interactions?

On one hand, of course - you can develop causal models formulated entirely at the psychological level (rewards, punishments, surprises, mood) that make falsifiable predictions and you can both perturb and measure these things to test those models.

On the other hand, we probably do need to take some care that we aren't confusing ourselves as we throw around that word "cause" interchangeably for things that physically interact and abstractions of those things.

Thoughts? I'm particularly curious about cases in which this type of abstraction has led researchers astray.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @PessoaBrain @albertcardona @katejjeffery @mieronen I don't understand. I can see it is not like biljart balls, but what is the difference? Being indirect? Or....?

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@albertcardona @PessoaBrain @katejjeffery @NicoleCRust @mieronen Hofstadter wrote "I am a strange loop" because he was frustrated that GEB was received well, but had no consequences or follow up in the field. (These are my words how I understood it). When I read GEB I thought it to be really something, but my understanding of his ideas was much helped by the second book.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@albertcardona @PessoaBrain @katejjeffery @NicoleCRust @mieronen In fact after GEB I did not understand a lot.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @katejjeffery @mieronen Do these psychologists study the brain and psychology?

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @katejjeffery @mieronen So we can simple ignore these psychologists or their arguments.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @katejjeffery @mieronen But how do they come together? Not by thinking seperately about them. Dualism...?

NicoleCRust, to random
@NicoleCRust@neuromatch.social avatar

Thoughts on these provocative ideas (about how research in psychology should proceed)?

The last author tipped me off to this one. Curious to hear impressions.

Beyond Playing 20 Questions with Nature: Integrative Experiment Design in the Social and Behavioral Sciences

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4284943

(also here, behind the BBS paywall: https://www.cambridge.org/core/journals/behavioral-and-brain-sciences/article/abs/beyond-playing-20-questions-with-nature-integrative-experiment-design-in-the-social-and-behavioral-sciences/7E0D34D5AE2EFB9C0902414C23E0C292)

The dominant paradigm of experiments in the social and behavioral sciences views an experiment as a test of a theory, where the theory is assumed to generalize beyond the experiment’s specific conditions. According to this view, which Alan Newell once characterized as “playing twenty questions with nature,” theory is advanced one experiment at a time, and the integration of disparate findings is assumed to happen via the scientific publishing process. In this article, we argue that the process of integration is at best inefficient, and at worst it does not, in fact, occur. We further show that the challenge of integration cannot be adequately addressed by recently proposed reforms that focus on the reliability and replicability of individual findings, nor simply by conducting more or larger experiments. Rather, the problem arises from the imprecise nature of social and behavioral theories and, consequently, a lack of commensurability across experiments conducted under different conditions. Therefore, researchers must fundamentally rethink how they design experiments and how the experiments relate to theory. We specifically describe an alternative framework, integrative experiment design, which intrinsically promotes commensurability and continuous integration of knowledge. In this paradigm, researchers explicitly map the design space of possible experiments associated with a given research question, embracing many potentially relevant theories rather than focusing on just one. The researchers then iteratively generate theories and test them with experiments explicitly sampled from the design space, allowing results to be integrated across experiments. Given recent methodological and technological developments, we conclude that this approach is feasible and would generate more-reliable, more-cumulative empirical and theoretical knowledge than the current paradigm—and with far greater efficiency.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @UlrikeHahn @jonny
@NicoleCRust
Beggs started out to think the cortex works at the edge of chaos. But that appeared not to be tenable. Not for the cortex, but more so for processes at the subcortical level.
Beggs JM (2022): The cortex and the critical point: understanding the power of emergence. Cambridge, Massachusetts, The MIT Press.

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @UlrikeHahn @jonny
The difference with the weather being a (near) chaotic (complex) system appears to be that living organisms (including brains) keep themselves far from equilibrium, while the processes in the atmosphere return to equilibrium, ie energy differences are cancelled out in due time. That is why a hurricane stops, while your brain never stops, until.....

MolemanPeter,
@MolemanPeter@neuromatch.social avatar
MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @UlrikeHahn @jonny Well, they seem to be the experts.

ekmiller, to random
@ekmiller@fediscience.org avatar

New paper! A universal pattern of brain wave frequencies. They are slower in deep cortical layers and faster in superficial layers. When something is this ubiquitous, you know it is doing something important.
https://picower.mit.edu/news/study-reveals-universal-pattern-brain-wave-frequencies

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@ekmiller Do the latter processes have a longer time-scale, ie last longer than the former? Longer I mean minutes and longer. Or does that make no sense at all?

NicoleCRust, to random
@NicoleCRust@neuromatch.social avatar

Done writing the book.

(Deep inhale).

~90K words. A few years of work. A transformative journey that did not end at all as I thought when I started. I'm grateful to have done it - what a privilege. A much bigger conceptual project than anything I've done up to this point.

I got to think intensely for a better part of a few years (in parallel to running a lab and teaching as a professor). Somehow there was not time for that before. I'm not exactly sure where I found it; I just did.

There will be many revisions going forward. And it won't hit the shelves anytime soon. But I'm going to pause and celebrate this moment, where every one of the bits are finally in place. I learned so much along the way. Even today, on the last day, I was fascinated, and I'm grateful. (That said, I'm also a bit tired).

What's the book about? A slice of the spirit behind it is captured here: https://www.thetransmitter.org/systems-neuroscience/is-the-brain-uncontrollable-like-the-weather/

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust Congrats, looking forward to it (also an ebook I hope)

UlrikeHahn, to random
@UlrikeHahn@fediscience.org avatar

New year, new blog post...

This time with some thoughts on social media for science discourse!

all comments welcome!

https://write.as/ulrikehahn/some-thoughts-on-social-media-for-science

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @UlrikeHahn @bwaber I am with you on all points

NicoleCRust, to Neuroscience
@NicoleCRust@neuromatch.social avatar

My new piece for @thetransmitter. Why is treating brain dysfunction so ENORMOUSLY challenging?

Because it amounts to controlling a complex system.

Drawing from the history of weather research, I pose the question: Can it even be done? And 14 experts in complex systems chime in. Would love to hear your thoughts as well!

https://www.thetransmitter.org/systems-neuroscience/is-the-brain-uncontrollable-like-the-weather/

MolemanPeter,
@MolemanPeter@neuromatch.social avatar

@NicoleCRust @thetransmitter Perhaps this is of interest to you in relation to the brain and chaos theory:
https://www.youtube.com/watch?v=mqzyKs2Qvug
Starting around min 36 about Steven Grossbergs work.

  • All
  • Subscribed
  • Moderated
  • Favorites
  • megavids
  • kavyap
  • DreamBathrooms
  • thenastyranch
  • magazineikmin
  • vwfavf
  • InstantRegret
  • Youngstown
  • ngwrru68w68
  • slotface
  • Durango
  • cisconetworking
  • tacticalgear
  • rosin
  • provamag3
  • everett
  • cubers
  • khanakhh
  • osvaldo12
  • mdbf
  • ethstaker
  • normalnudes
  • modclub
  • Leos
  • GTA5RPClips
  • tester
  • anitta
  • JUstTest
  • All magazines