Bioinformatics and Computational Biology

moorejh,
@moorejh@mastodon.online avatar
nicolaromano,
@nicolaromano@qoto.org avatar
MelBioInf,
@MelBioInf@genomic.social avatar

A final reminder: we are currently advertising three jobs! Applications close on 15 May. Details and links in the thread ⬇️ https://genomic.social/@MelBioInf/112295817677021230

sotneStatue,
@sotneStatue@fosstodon.org avatar

Today I'll be using #R for RNAseq analysis for the first time, wish me luck

numeredevs,
@numeredevs@fosstodon.org avatar

@sotneStatue Luck! Can you share a bit about your insights?

Lluis_Revilla,
@Lluis_Revilla@fosstodon.org avatar

@sotneStatue Good luck. I'm sure you'll find @Bioconductor packages very helpful! There is also a lot of materials on how to do it.
Pst if you use R the hashtag we use is usually . You might get more help if you post it with that hashtag 😉

bffo,
@bffo@mastodon.social avatar

You do in ? Elsewhere in the world? You lead a group? Maybe invite your students be volunteers at the largest International Bioinformatics Conference?

https://www.iscb.org/ismb2024/general-info/apply-to-be-event-staff

bffo,
@bffo@mastodon.social avatar

Remembering the first Canadian Workshop: … we used to use mouse pads back then! This was a useful one for those didn’t know their standard genetic code by heart

marcia,
@marcia@spore.social avatar

@bffo
I had one of those!

rmflight,
@rmflight@mastodon.social avatar

What RNA-Seq datasets are everyone using for RNA-Seq differential analysis workshops, using {DESeq2} or {limma} #RStats?

Two or three categories, and ideally a good (4 or 5+) number of replicates, human or mouse?

We have some new methods in ontology enrichment, and we really could use some more datasets to try them on.

I've found the {airways} dataset, and lung adenocarcinoma from {recount3} (as an easy pull). Looking for others. TIA.

#bioinformatics #RnaSeq

davelunt,
@davelunt@genomic.social avatar
MelBioInf,
@MelBioInf@genomic.social avatar

We are hiring! Melbourne Bioinformatics is expanding our team by recruiting into three new positions. This is your chance to become part of a dynamic team of expert bioinformaticians who are at the forefront of Australian training, outreach, and research.

All three roles are full-time, continuing positions based at the University of Melbourne's Parkville campus. Applications close 15 May 2024. For more information, including application instructions, follow the links below.

MelBioInf,
@MelBioInf@genomic.social avatar

Senior Bioinformatician, Bioinformatics Training (Level C)

You will lead our training operations, collaborate with external partners, and provide strategic oversight to ensure training targets are met effectively and efficiently.

https://jobs.unimelb.edu.au/en/job/916660/senior-bioinformatician-bioinformatics-training

Elendol,
@Elendol@hachyderm.io avatar

Having to deal with a vendor who prioritised integration with a LLM rather than having a decent codebase is quite something...

Elendol,
@Elendol@hachyderm.io avatar

And by decent, I am generous. I am starting to believe they never wrote software before, looked at the code of any other software before or even used software before...

computingnature,
@computingnature@neuromatch.social avatar
jonny,
@jonny@neuromatch.social avatar

@computingnature
Turns out domain specific models still rock. Love 2 see it ♥

computingnature,
@computingnature@neuromatch.social avatar

@albertcardona :) the challenge authors updated the test set since the challenge so we had to submit our masks and the winning team's masks to get the scores.

The winning Mediar team used the Cellpose flow approach (our code) and used a transformer instead of a CNN for prediction. On this dataset, it doesn't seem like the transformer improves performance. We also tested transformers on an even larger dataset and did not find a performance boost (blue and black curves) (from https://www.biorxiv.org/content/10.1101/2024.02.10.579780v2):

F2erron, French
@F2erron@fediscience.org avatar

Hello sugar people of the :fediverse: . My former collegue Bernard Henrissat now in 🇩🇰 is looking for a student in a Marie Sklodowska-Curie 🇪🇺 training network to work with him at the Technical University of Denmark. More info:
https://euraxess.ec.europa.eu/jobs/201030
The deadline for application is May 31st, 2024 and the job will start in November.

Skills desired: , general biology (++ ) and fluency in 🇬🇧.
Eligibility: the candidate should not have worked in 🇩🇰 before.

xgrau, Catalan
@xgrau@ecoevo.social avatar

We have two open positions to work on the bioinformatics team of the Biodiversity Cell Atlas initiative, at CRG (Barcelona).

Please contact Arnau Sebé if you're interested, as the deadline is next week — 10th of April!

Both positions are funded by the Moore Foundation.

naturepoker,
@naturepoker@genomic.social avatar

Yikes - this looks like a pretty serious issue. Especially considering high chance that the original author of the package might have been behind the backdoor attempt.

I know quite a few packages also need xz for compilation. Hate that we need to worry about stuff like this more from now on.

https://arstechnica.com/security/2024/03/backdoor-found-in-widely-used-linux-utility-breaks-encrypted-ssh-connections/

xahteiwi,
@xahteiwi@mastodon.social avatar

@naturepoker Um, this is a developing story but the idea that "the original author" of the library is behind the vulnerability injection is likely untrue.

lunareclipse,

anyone know some simple software for extracting tables from scientific papers (pdfs)?

#bioinformatics

nicolaromano,
@nicolaromano@qoto.org avatar
bioconductor,
@bioconductor@genomic.social avatar

🚀 Reminder: Opportunities

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Don’t miss your chance to contribute!

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