axoaxonic

axoaxonic, 4 months ago

The greater the KL-divergence, the longer the codeword of Shannon information, the longer the response time. Natural selection would choose rapid responses, so the KL-divergence is minimized: the probability density of the fluctuating intracellular ion concentration is kept as close to the mostly-constant probability density of the extracellular concentration as possible.

The huge range of different perturbations leading to intracellular ion concentration changes would increase the evolutionary pressure for complex and diverse ion channels under this principle

axoaxonic, 4 months ago

@BlackAzizAnansi Not really a secret just sad and nobody talks about it. My aunt kidnapped my grandma who was in late stage dementia, to manipulate her into leaving her inheritance to my aunt. Nobody knew where they were hiding until someone in the family hired a PI. When they were tracked down, the PI was met at the edge of the property by someone brandishing a gun, and the investigation ended there. My mom didn't know her mom had passed away until years after it happened

axoaxonic, 4 months ago

@BlackAzizAnansi My grandma was a single mother working as a nurse in LA, but got some money from marrying the guy who invented the little plastic clamp tool that helps people open jars. Guess it was enough to corrupt my aunt and cause a lot of grief in my mom's family

axoaxonic, 5 months ago

@jonny The whole of something contains its core elements. Jumping into the advanced side early really makes the structural and basic stuff clear because you see how it connects to everything else, and why it's necessary. It always feels more meaningful and makes me understand something better, even though I'm paradoxically more confused in the process. Glad you're bringing this style to your teaching

I was inspired to study this way by reading Kató Lomb’s "Polyglot: How I Learn Languages" https://www.tesl-ej.org/books/lomb-2nd-Ed.pdf
She started learning languages after 30 and became a professional translator and interpreter in 16 of them

axoaxonic, 5 months ago

@jonny It's a great book about language learning but also about learning in general I think. It's been a while since I read it though.

Also, the world of polyglots in general is really interesting to explore, like Alexander Arguelles who knows 50+ languages https://www.youtube.com/@ProfASAr

and LaoShu505000 who gamified language learning, "leveling up" by walking around with a GoPro talking to random people in their native languages https://www.youtube.com/@laoshu505000

axoaxonic, 5 months ago

@jonny fern accomplice

axoaxonic, 5 months ago

@jonny I tried reading it a few years ago but mostly just marveled at the wall of opaque equations. apparently lots of pro mathematicians can't understand it either. Love the aesthetic of Mochizuki's website also

axoaxonic, 5 months ago

@jonny I remember watching a video lecture where during the Q & A Misha Gromov was talking about how he liked how cryptic and hard to understand advanced math was, because he likes the pursuit of the mysterious, and a different mathematician was saying the inaccessibility was a big problem. It might be so complex of a concept that it's difficult to compress, but if it is meant to be a meaningful and useful contribution people have to be able to understand it for sure.

I want to try re-reading it though just to enjoy wandering around in the confusing dense landscape

[edit: I mean re-reading the original https://www.kurims.kyoto-u.ac.jp/~motizuki/Inter-universal%20Teichmuller%20Theory%20I.pdf ]

axoaxonic, 6 months ago

@ttpphd The link to the SfN poster in the article directs to a login screen, do you know if there's another url or doi for it? I want to know the details on early life stress + TBI because I've experienced both

axoaxonic, 6 months ago

@elduvelle Been wearing [K]N95 masks indoors always, only ordering food to go or eating at outdoor tables, and I haven't been sick at all in almost 4 years

axoaxonic, 6 months ago

@elduvelle Hoping the same for you. I wish more public places would use air filters, especially restaurants

axoaxonic, 6 months ago

Wondering what could be learned by considering the PFC through the lens of nonautonomous dynamical systems theory, which are dynamical systems that explicitly depend on time

https://link.springer.com/book/10.1007/978-3-319-03080-7

https://bookstore.ams.org/surv-176

https://link.springer.com/book/10.1007/978-3-030-34292-0

axoaxonic, 6 months ago

@NicoleCRust @beneuroscience @MolemanPeter @debivort @knutson_brain @PessoaBrain @DrYohanJohn The possibility of contextuality in physics being unrelated to what Juarrero means by context is why I followed up by linking the quote from Abramsky's work on the logic of (quantum) contextuality with the Brain Inspired interview of Alicia Juarrero.

She says context dependence is necessary for the emergence of causal and coherent structures in the brain and elsewhere, and links her ideas to physics but doesn't seem to be coming from quantum physics, where according to the Kochen-Specker theorem, context dependence is necessary for quantum mechanics https://en.m.wikipedia.org/wiki/Kochen%E2%80%93Specker_theorem

The Sulis paper argues that contextuality from QM should extend to classical physics via non-Kolmogorov probability:

"Perhaps, at times, the classical realm can also be discrete, non-Kolmogorov, and contextual. Contextuality at the classical level was recognized even by Kolmogorov [9] when he formulated the axioms of probability theory. He stated explicitly that all probability measures needed to be linked to specific contexts, and the ability to combine such measures across distinct contexts was not a given; rather, there are precise mathematical conditions that must be met in order for that to be possible [10]. Unfortunately, this seems to have been forgotten during a century of usage."

I learned about contextuality through a surface level exploration of quantum computing, which made me think about context dependence in general regarding brain/mind/cognition, but I don't know how useful ideas of contextuality in QM could be in informing classical dynamical systems models of contextuality in the brain. Sulis' attempt is interesting and pretty much the only one I could find

axoaxonic, 6 months ago

@MolemanPeter @NicoleCRust @beneuroscience @debivort @knutson_brain @PessoaBrain @DrYohanJohn Yes it seems to be the same point, that context dependence is well founded and formalized on the quantum scale but is likely a feature of classical systems too

axoaxonic, 6 months ago

@NicoleCRust @MolemanPeter @beneuroscience @debivort @knutson_brain @PessoaBrain @DrYohanJohn Thank you again for your feedback and encouragement. I have so much to write about, a "neuro ideas" txt file with over a thousand lines that could turn into many essays and projects, all I need now is to find balance and energy to get things together better.

I really don't see how it couldn't be a part of the classical realm, i just threw in "likely" on the off chance that it doesn't for some bizarre reason. I prefer to leave some room to be wrong but context exists in everyday experience, it's definitely real

axoaxonic, 6 months ago

@teixi I learned about OpenBCI a while ago, they were one of the first. After looking into their products I found out that a DIY EEG system can be made with some electrodes and a relatively simple amplifier https://www.biosignals.org.uk/#build_your_own_bio-amplifier for way less money. The hard part would be getting the electrode placement and conduction right, then the rest is software related signal processing

axoaxonic, 6 months ago

@jonny Hell yes I'm so ready for neurotech-flapper fusion fashion