Panadol / Paracetamol / Tylenol / Acetaminophen / C8H9NO2 is exceptionally easy to overdose on. I've done it accidentally a couple of times. It causes liver damage at even lower overdoses, you really don't want that.
The maximum dosage is 1g every 4 to 6 hours, maximum total 4g a day. I am no doctor but I strongly recommend 6+ hours between doses (I set a timer) and I try very hard to not get to 3g or above per day. It's even worse that plenty of medications just throw it in to the mix casually.
Unfortunately as the only first line of defence I have against pain, I cannot avoid it altogether. Redflags for me were light abdominal pain and yellowing of skin under eyes. Plus fatigue, but that's normal in my world.
Definitely ease up on it if you can, especially if you've been taking it for more than a week regularly. If you can't reduce usage/dose, then be much more generous with the minimum gap between doses, especially if your liver is already under a bit of pressure from other meds or alcohol.
Pain sucks, and pain management causes pain. Sorry about the dental stuff, my issue isn't teeth but I know that is no fun too.
I accidentally overdosed on acetaminophen after a surgery once. Doctor forgot to tell me (or I was still high when he told me) he gave me acetaminophen during/after the surgery. I thought I still could take up to 4g that day. A few hours after the surgery, the pain started to kick in so I took some acetaminophen. Ended up vomiting uncontrollably.
Everything. Literally everything can be fatal in large enough quantities. Quote from one of my chemistry professors: “there are no lethal substances, only lethal doses”
Remember the Wii craze in 2007? There was a radio competition called Hold Your Wee for a Wii in which the contestants had to drink throughout the day without going for a piss. One died.
Acetaminophen/Paracetamol. The safe therapeutic dose is very close to the toxic dose. While most people don’t intentionally overdose, at least not for treating illness symptoms, the problem arises when they take multiple medications that all contain acetaminophen, following the label for all of them can easily net you a toxic dose.
It’s been said a lot that light alcohol consumption is actually good for your health, but this is not actually true. It improves some health outcomes but the benefits are outweighed by the risk. There is no safe amount of alcohol consumption.
Hilarious how the alcohol lobby scratched around for years looking for a good news story about alcohol and came back with some weak sauce link between red wine and heart disease. Meanwhile, 50% of reported sexual assaults are linked with alcohol. Probably more like 80%. How is alcohol legal and LSD is a schedule 1 substance? There is no lethal dose and has been discovered as a treatment for resistant depression and PTSD, OCD, etc. Our drug laws are completely wack.
The real elephant in the room is alcohol is much more destructive and just as addictive than measurable controlled doses of opoids, and also equally if not more destructive than stimulants like amphetamines and cocaine. It’s basically the worst drug in every metric. If every alcoholic got their drinks replaced with MS Contin and or weed, the strain on the health system would be much less. Not to mention all the other negative externalities related to alcohol intoxication.
I say all this as someone who drinks. I am going to ensure my child is aware of all the negatives at an early age and be open to discussion about substances. People either like or dislike alcohol, and the people who like it have no self control. It’s a stupid drug, I wish I was never introduced the way I was.
Don’t even get me started on the alcohol companies producing alcoholic mountain Dew, freeze pops and Sunny D… and they have the gall to ban flavored vapes haha.
I have a feeling that alcohol will come to be viewed in a similar way we now look at religion. It’s a cultural artefact from an ignorant time. It serves some purpose and there is a basic utility but overall it has a toxic effect. I hear that research is ongoing to find a credible alternative molecule without the deleterious health outcomes.
Western society has a generally incoherent and childish attitude to substances. Some are viewed as evil e.g. heroin but when this drug turns up in a therapeutic setting, it inexplicably becomes medicinal i.e. diacetylmorphine, which is the acceptable face of heroin, used for terminal cancer treatment.
No substance should be viewed as either panacea or disaster. They are tools that we can use when the time and place is appropriate. We ought to educate ourselves and have honest conversations. Prohibition is getting in the way of this effort and it must go. In it’s place we install education, healthcare and hygiene for the mind.
Happy to find a fellow psychonaut. What’s your next project in this area? I am considering a psychedelic voyage to the Netherlands.
Haha, I am a bit on the older side and basically have took all my trips. I have a hallucinagen stash for every couple years with my wife, but that’s about it. I have tried almost everything at this point.
I would like to take one of those camel desert treks, where before bed you get to smoke opium and then cuddle with a camel for warmth while you sleep. That sounds like the best nights sleep possible… Although it’s relatively weak opiate, opium is supposedly a very unique high compared to other opiates. My uncle did it decades ago and he said it was one of the best times of his life. Unfortunately there are few countries that offer the experience, and a few of them are going through very dangerous internal strife. (I mean the countries don’t support the drug use, they just turn a blind eye)
I’ve had a few trips over the years but never used them in a therapeutic setting. My mental health has become more fragile as I’ve got older and I took up meditation over the last year in an effort to improve it. They say that meditation works by stilling something called the Default Mode Network and psychedelic drugs also work on this process in your mind but in a completely different way. The plan is to take a Heroic Dose of mushrooms (people say 5g of dry shrooms) and then do an assimilation session afterwards. The session is guided by an experienced person.
Your camel adventure sounds great but all the camels I met so far have been hella grumpy. I would be worried that they were going to bite me for snoring too much. Well, that’s what my wife does.
Heartbeats. 60 - 70 is good (you can get away with lower if you’re fit, but anything below 40 is bad), and anything above 180 - 200+ tends to be quite bad for your health.
Yes. Anything above 220 tend to be quite bad for your health, since there’s not enough time for your heart’s chambers to fill at that speed.
As usual with biology, there’s exceptions to the rule, but for your average human, anything past that means that there’s usually not enough blood coming out to keep you alive at those speeds, and your heart may as well not be beating at all, for all the good it does.
It’s similar to why Ventricular Fibrillation is bad for you, since it’s a similar problem (but only limited to the two main pumping chambers/ventricles of the heart, rather than including the atria).
Took a Hazmat class today and the big thing they drilled into our heads was “Everything is toxic at scale.” So make anything you want and there is an IDLH concentration.
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