cyrilpedia

cyrilpedia, 4 months ago to random

"The rate of serious medical complications increased in hospitals after they were purchased by private equity investment firms, according to a major study of the effects of such acquisitions on patient care in recent years."

https://www.nytimes.com/2023/12/26/upshot/hospitals-medical-errors.html

cyrilpedia, 4 months ago to random

'The book that gives us Calvino the romantic and Calvino the craftsman in equal measure is “If on a Winter’s Night a Traveler.” It is the book that makes people fall in love with Calvino, because it is a book about falling in love through reading—specifically, “reading Italo Calvino’s new novel, If on a winter’s night a traveler.”' (Illustration by Daniele Castellano)

https://www.newyorker.com/magazine/2023/03/06/the-worlds-of-italo-calvino

cyrilpedia, 4 months ago to random

"However, the metrics generally used to evaluate protein structure prediction methods—including all of those used in CASP—focus on the overall accuracy of predicted structures, rather than on their utility in predicting ligand binding. This has left the large community of academic and industrial researchers who wish to use protein structures to design drugs and other ligands unsure of whether, when, and how to use the new structural models. Improvements in protein structure prediction are widely assumed to lead to better models of ligand-binding pockets and thus more accurate predictions of ligand binding (Beuming and Sherman, 2012; Bordogna et al., 2011; Erickson et al., 2004), but to what extent do these assumptions hold?"

https://elifesciences.org/articles/89386

cyrilpedia, 4 months ago to random

'It involves a debut author with a lot of buzz, lies, clumsy alibis, “review bombing,” a long and sordid confession — and, of course, Goodreads. Because whenever there is a meltdown in publishing, Goodreads, the Amazon-owned site that bills itself as “the largest site for readers and book recommendations,” is reliably at the center of it.'

https://www.nytimes.com/2023/12/24/opinion/goodreads-books-reviews.html

cyrilpedia, 5 months ago to random French

Fake news BC

"En plein Sénat, Caton laisse échapper quelques figues gorgées de jus, comme tombées par mégarde des plis de sa toge. Lorsque ses collègues s'extasient, Caton jure qu'il les ramène de Carthage –et que si elles sont si appétissantes, c'est parce que l'ennemie jurée n'est qu'à trois jours de Rome. Caton a menti: la traversée prend au mieux six jours et il y a toutes les chances que les fameuses figues soient venues de ses propres plantations. Mais qu'importe: le souvenir d'Hannibal est ravivé. Dans le doute, il faut raser Carthage."

https://www.slate.fr/culture/histoires-sans-fin/carthage-incendie-scipion-emilien-rome-resistance

cuttlefish, 5 months ago to random

mr president a second gay sex tape has hit the capitol

cyrilpedia, 5 months ago to random

"The disruption this year in supplies of key chemotherapy drugs has realized the worst fears of patients — and of the broader health system — because some people with aggressive cancers have been unable to get the treatment they need."

https://www.nytimes.com/2023/12/19/health/cancer-drug-shortage.html

cyrilpedia, 5 months ago to random

Great piece - I expected the neglected researchers, the public health effects of deprivation, the normally peace-loving organism thrust into the role of pathogen, British imperialism as the secret ingredient that makes any problem worse... But I did not see the volcano coming :)

(via. The Browser)

https://openthemagazine.com/features/living/amnesia-hour/?ref=thebrowser.com

cyrilpedia, 5 months ago to random

"When the newspaper El País timed the same 8km journey across Barcelona by car, motorcycle, bicycle and public transport, the motorbike won, followed 2.5 minutes later by public transport, with the bicycle third and the car last."

https://www.theguardian.com/cities/2023/dec/18/bollards-and-superblocks-how-europes-cities-are-turning-on-the-car

cyrilpedia, 5 months ago to random

"Netanyahu was building alliances with the illiberal governments of Central European countries, such as Poland and Hungary, in part to prevent an anti-occupation consensus from solidifying in the European Union. For this, he was willing to lie about the Holocaust."

https://www.newyorker.com/news/the-weekend-essay/in-the-shadow-of-the-holocaust

cyrilpedia, 5 months ago to random

"The bulk of 2023’s retractions were from journals owned by Hindawi, a London-based subsidiary of the publisher Wiley (see ‘A bumper year for retractions’). So far this year, Hindawi journals have pulled more than 8,000 articles, citing factors such as “concerns that the peer review process has been compromised” and “systematic manipulation of the publication and peer-review process”, after investigations prompted by internal editors and by research-integrity sleuths who raised questions about incoherent text and irrelevant references in thousands of papers."

https://www.nature.com/articles/d41586-023-03974-8

cyrilpedia, 5 months ago to random

'Another implication of their study is that our ancestors enjoyed a malaria-free existence right up until the neolithic transition 10,000 years ago when, coincident with the shift from nomadic to agrarian lifestyles, Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, mutated to target Neu5Ac so abundantly present on human cells. It is thought that our more agricultural lifestyle made humans more vulnerable to the malaria-carrying mosquitoes that bred in stagnant pools near settlements.'

https://www.theguardian.com/science/2023/dec/10/sugar-coating-cells-illness-pathogens-evolutions-glycans-sialic-acids

cyrilpedia, 5 months ago to random

"The main and interesting conclusion in the abstract is that of the 45% of alumni not continuing in academic research, one third does industry research and one third is in a science-related profession."

https://elifesciences.org/articles/78706#sa1

cyrilpedia, 5 months ago to random

'He told me he had started writing the song for a prospective musical version of Nosferatu years before, but never finished it. Around the time we were recording, Meat Loaf had lost his voice, and after it was a hit he always used to say: “Dang. That song should have been mine!”

https://www.theguardian.com/culture/2023/nov/27/bonnie-tyler-total-eclipse-of-the-heart-nosferatu-musical

cyrilpedia, 5 months ago to random

"Large outbreaks of diseases that primarily kill children are spreading around the world, a grim legacy of disruptions to health systems during the Covid-19 pandemic that have left more than 60 million children without a single dose of standard childhood vaccines."

https://www.nytimes.com/2023/11/25/health/vaccines-children-zero-dose.html

cyrilpedia, 6 months ago to random

"Safety teams within the company pushed to slow things down. These teams worked to refine ChatGPT to refuse certain types of abusive requests and to respond to other queries with more appropriate answers. But they struggled to build features such as an automated function that would ban users who repeatedly abused ChatGPT. In contrast, the company’s product side wanted to build on the momentum and double down on commercialization."

https://www.theatlantic.com/technology/archive/2023/11/sam-altman-open-ai-chatgpt-chaos/676050/

cyrilpedia, 6 months ago to random

"Rio de Janeiro, Brazil
People cool off at Leme beach amid a heatwave. Air temperatures surpassed 50C in some places and red warnings were issued across 3,000 cities"
Photograph: Ricardo Moraes/Reuters

https://www.theguardian.com/news/gallery/2023/nov/19/a-heatwave-snow-and-a-celebrity-selfie-photos-of-the-weekend

cyrilpedia, 6 months ago to random

"Chronic viral infections are known to accelerate immune aging and to induce immune senescence (21, 22). We have shown that among 206 viruses with human tropism, only CMV seropositivity was associated with senescence of CD8+ T cells in patients with aNSCLC."
#Immunology #TumorImmunology #Immunotherapy

https://www.science.org/doi/full/10.1126/sciadv.adh0708

cyrilpedia, 6 months ago to random

"Scientists need the time and security to investigate questions that may lead to dead ends or, alternatively, yield new understandings of the world. This rarely happens if their research is driven by short-term responses to market demands."

https://hedgehogreview.com/issues/the-cultural-contradictions-of-modern-science/articles/trivial-pursuits-the-decline-of-scientific-research

cyrilpedia, 6 months ago to random

'Deforestation in the Amazon rainforest in Brazil fell to a five-year low, the country’s National Institute of Space Research announced on Thursday, a sign that Brazil, which has the biggest share of tropical forest in the world, was making progress on its pledge to halt all deforestation by the end of the decade.'

https://www.nytimes.com/2023/11/09/climate/amazon-deforestation.html

cyrilpedia, 6 months ago to random

'More than half of all British defence exports go to the Middle East – but to Saudi Arabia rather than Israel. Human rights organisations, including Amnesty International, accuse BAESystems of being party to Saudi war crimes in Yemen, where BAE-supplied (and serviced) fighters have bombed schools and hospitals.'

https://www.lrb.co.uk/the-paper/v45/n22/james-butler/up-in-arms

cyrilpedia, 6 months ago to random

"At least two million low-income children have lost health insurance since the end of a federal policy that guaranteed coverage through Medicaid earlier in the Covid-19 pandemic, according to newanalyses by researchers at the Georgetown Center for Children and Families and KFF, a health policy research organization."

https://www.nytimes.com/2023/11/09/health/medicaid-children-lost-coverage.html

cyrilpedia, 6 months ago to random

"When bats fly, their metabolism can rev up to 15 to 16 times above its resting state; their heart rate may soar above 1,000 beats per minute; their body temperature can exceed 105 degrees Fahrenheit, effectively plunging the animals into an epic fever state. Put all of that on virtually any other mammal, and their body would likely be overwhelmed by the blaze of extreme inflammation, the toxic by-products of their metabolism effectively rending cells apart."

https://www.theatlantic.com/health/archive/2023/11/bat-disease-virus-health-aging/675943/

cyrilpedia, 6 months ago to random

"The NLOS that spits out the Transplant Benefit Scores is one of dozens of algorithms in use in healthcare systems around the world. These applied statistical systems are used by physicians and hospitals to aid decisions such as who receives heart surgery and organ transplantation, which patients are at the highest risk of surgical complications, and in diagnosing cancers and brain injury. The intent behind predictive algorithms, like the NLOS, is to make consequential decisions fairer."

https://www.ft.com/content/5125c83a-b82b-40c5-8b35-99579e087951