@cyrilpedia@qoto.org avatar

cyrilpedia

@cyrilpedia@qoto.org

I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com

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cyrilpedia, to random
@cyrilpedia@qoto.org avatar

'We are not, however, the first generation to confront the challenge of authoritarian propaganda. And as I looked for past experiences to inform our own, I discovered a British second world war media operation that managed to engage huge audiences who had been loyal to the Nazis and undermine their faith in Hitler’s regime. If we think reaching people in “echo chambers” today is tough, think about how hard it was to persuade Germans to trust the people who were literally trying to kill them.'

https://www.theguardian.com/books/2024/mar/02/the-man-who-tricked-nazi-germany-lessons-from-the-past-on-how-to-beat-disinformation

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

'Here’s a recent paper with a rare use of an “antibiotic antibody” idea. I was writing here not long ago about a new antibiotic candidate that targets Acinetobacter baumannii, which is a major human pathogen (and especially so in hospital-derived infections). This new work details the generation of an antibody to an important part of the A. baumannii outer membrane, pseudaminic acid. That’s an unusual amino-sugar compound that is not found in mammals at all, so it’s a pretty clean target.'

https://www.science.org/content/blog-post/antibodies-everywhere

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

"When asked by Nature how the papers made it through review, a Sage spokesperson responded that the publisher relies on journal editors to make individual decisions on submitted works based on the evaluations of peer reviewers. In its retraction notice, Sage said that it discovered one peer reviewer who had evaluated the three papers was affiliated with an anti-abortion organization."

https://www.nature.com/articles/d41586-024-00556-0?utm_source=Live+Audience&utm_campaign=ad2ff535f6-briefing-dy-20240228&utm_medium=email&utm_term=0_b27a691814-ad2ff535f6-49733304

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

The Mole & Velazquez

"And, of course, who gets to judge? Who would we want to judge? Well, the little five-year-old girl in Las Meninas is giving us the most mischievous and heart-felt smile. A smile that speaks of respect and love, but also self-confidence born of the strength that emanates from the center of her attention (the royal couple, perhaps, or we, who stand in their place). Maybe it would all be worth it if our scientific `children', our students and trainees, were to look at us that way. Maybe that would be something worth striving for."

https://journals.biologists.com/jcs/article/117/9/1615/28076/Eyes-on-the-prize

cyrilpedia, to conservative
@cyrilpedia@qoto.org avatar

'Co-designing Biodiversity Assessments' (São Paulo)
Application deadline March 11

"The central objective of SPSAS Co-designing Biodiversity Assessments is to empower young scientists and environmental technicians to design, obtain, and analyze biodiversity data suitable for supporting effective environmental action programs and policies.
We aim to encompass biodiversity of key taxa in their genetic, phylogenetic, functional, and sociocultural dimensions, developing comprehensive and adaptable assessment procedures that meet real-world demands."

https://espca.ib.unicamp.br/en/home-english/

Ruth_Mottram, to climate
@Ruth_Mottram@fediscience.org avatar

A survey in European countries showed 69% of people would be willing to give up 1% of their income each month to fight - but most people believe they are in a minority who would.
How to do climate policy in the age of the green backlash - https://on.ft.com/3urWMxH via @FT

cyrilpedia,
@cyrilpedia@qoto.org avatar

@largess @Ruth_Mottram Every cent of government subsidy for airlines has to move to rail (and to facilitate the transition of airline employees)

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

'Groups seeking to harness mind-altering substances including MDMA, psilocybin mushrooms and 5-MeO-DMT, a hallucinogen found in desert toad secretions, raised at least $163mn across five deals in January, according to PitchBook and company data.'

https://www.ft.com/content/4a2e856c-4736-4b8b-9323-583bb1dbe8f4

cyrilpedia, to climate
@cyrilpedia@qoto.org avatar

A bad outbreak of #dengue in Brazil - and a warning that climate change is shifting the vector's range.

"The World Health Organization has warned that dengue is rapidly becoming an urgent global health problem, with a record number of cases last year and outbreaks in places, such as France, that have historically never reported the disease."
#Virology #InfectiousDisease #climatechange

https://www.nytimes.com/2024/02/10/health/dengue-brazil-americas.html

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

'Imagine my surprise when I received reviews on a submitted paper declaring that it was the work of ChatGPT. One reviewer wrote that it was “obviously ChatGPT”, and the handling editor vaguely agreed, saying that they found “the writing style unusual”. Surprise was just one emotion I experienced; I also felt shock, dismay and a flood of confusion and alarm. Given how much work I put into writing, it was a blow to be accused of being a chatbot — especially without any evidence.'

https://www.nature.com/articles/d41586-024-00349-5?utm_source=linkedin&utm_medium=organic_social&utm_content=null&utm_campaign=CONR_JRNLS_AWA1_GL_PCOM_SMEDA_NATUREPORTFOLIO

cyrilpedia,
@cyrilpedia@qoto.org avatar

@MCDuncanLab As a former editor, I'd add that this is also a failure of journal editors - who should review reviews (and reviewers).

cyrilpedia,
@cyrilpedia@qoto.org avatar

@MCDuncanLab A good editor will step in when the reviewers are taking personal shots, making inappropriate comments etc Sometime it can even undermine a review that makes important points about the work. There's a good case in this episode of the , where then @embojournal editor Karin Dumstrei & I discussed one such case with the authors. https://www.embo.org/podcasts/the-band-and-the-rhythm/

cyrilpedia,
@cyrilpedia@qoto.org avatar

@MCDuncanLab There are certainly cases where both editors and reviewers fail at their respective roles. I'm a fan of transparent reviews, one experience that came up often at Review Commons was authors and reviewers praising the more positive overall tone of comment vs conventional journal-based peer review.

cyrilpedia,
@cyrilpedia@qoto.org avatar

@MCDuncanLab I wish I could recall the original source, but someone had commented a while back that it starts from the hypercritical approach nurtured at many lab meetings & journal clubs - the comment was something along the lines of "we are training pitbulls and then are shocked when they tear manuscripts apart".

cyrilpedia,
@cyrilpedia@qoto.org avatar

@IanSudbery @MCDuncanLab Peer review workshops making use of real-world reviews are a good starting point (there is always the individual mentoring, but this is entirely up to each PI). One initiative that I heard from a few labs & really liked is that they discuss preprints in lab journal clubs and then write up the comments to send to the authors.

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

'By then, Einstein was public enemy No 1 in Germany. In May 1933, a brochure entitled Jews Are Watching You accused Einstein of “lying atrocity propaganda against Adolf Hitler”. Under his picture, it stated: “Not yet hanged.”

https://www.theguardian.com/science/2024/feb/10/einstein-on-the-run-how-the-worlds-greatest-scientist-hid-from-nazis-in-a-norfolk-hut

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

The Sting

"Intrigued by a citation-boosting service that we unravelled during our investigation, we contacted the service while undercover as a fictional author, and managed to purchase 50 citations."

https://arxiv.org/abs/2402.04607

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

'The best piece of advice I've had was from John Wallingford, and it was simple: “Read and learn how to write.” Learning how to write will save you a lot of time in a scientific or research career. Writing fast, writing well, writing clearly and concisely in a way makes people excited about your research – this is a skill that will definitely make your life easier.'

https://journals.biologists.com/jcs/article/137/3/jcs261929/342718/Cell-scientist-to-watch-Jakub-Sedzinski

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

That's not a profit margin. That's👇 a profit margin

"Relx does not disclose figures for specific journals but reported £2.9bn revenues in 2022 for all scientific, technical and medical products, with an operating profit of £1.1bn."

https://www.ft.com/content/33e41e46-0d5d-480b-ad08-009da434c52f

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

“If you have growing numbers of researchers who are being strongly incentivised to publish just for the sake of publishing, while we have a growing number of journals making money from publishing the resulting articles, you have a perfect storm,” said Professor Marcus Munafo of Bristol University. “That is exactly what we have now.”

https://www.theguardian.com/science/2024/feb/03/the-situation-has-become-appalling-fake-scientific-papers-push-research-credibility-to-crisis-point

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

"For these reasons, we hypothesize that PTMs could have been selected throughout evolution at the flanks of aggregation-prone regions as an intrinsic factor to protect proteins against aggregation, thus expanding the current repertoire of aggregation gatekeepers."

https://www.science.org/doi/10.1126/sciadv.adk8173

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

"This nightmare illness doesn’t yet exist. But for inspiration, Napper needs to look only at the very real contagion in his own lab: chronic wasting disease (CWD), a highly lethal, highly contagious that is devastating North America’s deer, elk, and other cervids."

https://www.theatlantic.com/science/archive/2024/02/deer-chronic-wasting-disease-prions-spillover-people/677307/

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

"Driverless cars are often called autonomous vehicles – but driving isn’t an autonomous activity. It’s a co-operative social activity, in which part of the job of whoever’s behind the wheel is to communicate with others on the road."

  • Rebecca Solnit

https://www.lrb.co.uk/the-paper/v46/n03/rebecca-solnit/in-the-shadow-of-silicon-valley

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

"In 2022, there were 941 reported cases of measles in the World Health Organization’s European region. Over just the first 10 months of last year, according to an alarming bulletin the W.H.O. issued in mid-December, there were more than 30,000."

https://www.nytimes.com/2024/02/01/opinion/health/measels-europe-vaccination.html

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

"Infections are the second-leading cause of death among cancer patients, and lead to one in five being hospitalised during treatment. Given that many cancer therapies weaken the immune system, making patients more susceptible to infections, this is to some extent to be expected. But increasingly clinicians see infections that are becoming drug-resistant — antibiotics once effective against them no longer work. Without new and effective antibiotics, this is only going to get worse, with more people surviving cancer only to die of an infection that was previously treatable."

https://www.ft.com/content/196fc183-cd54-461c-a3dc-215bfbcd90fa

cyrilpedia, to random
@cyrilpedia@qoto.org avatar

"Metastatic cancers (those that have spread beyond the organ where they originated) account for around 67–90% of cancer deaths2,3, and are almost always treated systemically, meaning with drugs that enter the bloodstream. To improve treatments for people with metastatic cancer, the community urgently needs to shift from using organ-based classifications of cancer to using molecular-based ones. This will require radical changes in how medical oncology is structured, conducted and taught."

https://www.nature.com/articles/d41586-024-00216-3?utm_medium=Social&utm_campaign=nature&utm_source=Twitter&error=cookies_not_supported&code=17a5c0c0-698b-485d-9227-07079517b9c4#Echobox=1706725921

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