A biotechnology company creating living tissue from a person's stem cells says it received FDA clearance for a clinical trial of its replacement knee cartilage.
A developer of treatments for cancer and autoimmune disorders from stem cells says FDA cleared its request to start a clinical trial of its therapy for systemic lupus erythematosus.
This Very Short Introduction introduces stem cells, exploring what they are, and what scientists do with them. Introducing the different types of stem cells, Jonathan Slack explains how they can be used to treat diseases such as retinal degeneration, diabetes, Parkinson's disease, heart disease, and spinal trauma.
A company with a process to generate new thymus tissue for immune system functions is receiving a $37 million award from the government's health breakthrough agency.
Newbie question: After coating culture dishes, can we put Matrigel, Synthemax, etc. to new dishes for another round? It'd be a cool way increase #sustainability 💚 & save💰.
ChatGPT says no🙁, but what's the real-world lab take on this?
Do you want to identify the neighbours of your favourite cells but are unsure where to start?
Check out our Primer, just out in @Dev_journal , for an overview of synthetic neighbour-labelling systems and of how they can be used in developmental settings.
Huge thanks to @CellySally, Tamina Lebek and Guillaume Blin for a real fun writing experience!
Researchers from university labs in the U.K. are developing models of brain cell interactions using a company's synthetic human cells derived from stem cells.
Researchers use stem cells to generate human neurons resembling those in the brain that control breathing during opioid reactions, for eventual chip devices to test overdose therapies.
I'm a synthetic developmental biologist at The University of Edinburgh.
I'm interested in understanding how cells influence their neighbours in mammalian models of #DevBio and disease.
I use #SynBio to identify neighbours of cells of interest (e.g. healthy neighbours of mutant cells), and to engineer cell behaviour in response to these interactions.
I do this in pluripotent #StemCells and their derivatives.
I look forward to keeping up with everyone's cool research!
Health authorities in Sweden authorized the start of a clinical trial testing insulin-producing cells from donors engineered to prevent immune reactions in people with type 1 diabetes.
> A research team [..] has created complete models of human embryos from stem cells cultured in the lab—and managed to grow them outside the womb up to day 14. As reported today in Nature, these synthetic #embryo models had all the structures and compartments characteristic of this stage, including the placenta, yolk sac, chorionic sac and other external tissues that ensure the models' dynamic and adequate growth. https://phys.org/news/2023-09-human-embryo-grown-stem-cells.html#stemcells
Scientists grow whole model of human embryo, without sperm or egg (www.bbc.com)
The research helps understanding of the earliest moments of life and the reasons behind infertility.