Using CRISPR gene-editing technology, scientists have successfully snipped out HIV from infected cells. Much more work needs to be done before this could possibly be used in people, but it’s a start...
Mismatches can induce unwanted cleavage events and off-target effects in CRISPR-Cas12a-based #GeneEditing. This #PLOSBiology study describes a high-fidelity AsCas12a variant with improved targeting specificity.
Today the FDA approved 2 gene therapies to treat sickle cell disease, including the first CRISPR-based therapy.
Bluebird Bio, who has the ~$1M more expensive and not-CRISPR therapy, has a single card left to play in this competition: It's been conducting a year-long dress rehearsal for this moment
A developer of treatments for cancer and autoimmune disorders from stem cells says FDA cleared its request to start a clinical trial of its therapy for systemic lupus erythematosus.
A new company is underway that says it adapts the gene editing technique Crispr to make detecting nucleic acid targets like DNA or RNA faster and simpler.
Stable shelf life is incredibly important for food distribution around the world and reducing overall food waste.
Similar to non-browning features in other crops like the Arctic Apple, Japanese scientists at Tsukuba University have used CRISPR to knockout an ethylene production gene responsible for fruit ripening.
An excellent article about the #EU European Commission's #GMO#deregulation proposal, by the journalist, former #MEP, and expert on GMOs Benedikt Haerlin
In a nutshell--based on one of the best articles I've read in weeks:
@EU_Commission makes patronizing #GMO legislation proposal, signifying a paradigm shift that resembles #Russian roulette in #genetics of edible plants. #Crisperisation will permit non-labelelling of GMOs.
Mosquitoes made immune to malaria could help stamp out the disease | … (archive.is)
A gene-editing technique makes mosquitoes produce antibodies against the malaria parasite, which could mean cases in people are also slashed
EU plans to relax #GMO restrictions to help farmers adapt to climate change (www.ft.com)
Controls could be eased on plants ranging from wheat able to withstand drought to fungus-resistant tomatoes