And this article is a prime example of when #science becomes "flashy" at the expense of correctness. No journalists to blame. This is the authors', the editors', the reviewers' and the magazine's fault.
Back in the late 90's, the human Y chromosome was thought to host about 3 genes: the SRY for sex determination, a gene for hair in the ears, and a MHC receptor for olfaction. That's how off the field was when relying on sparse sampling.
So I got a new paper published! “Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits”. #genomics#paper#eQTLs#pQTLs#metabolites#GWAS#disease
I wrote a thread on our findings on the other place for those inclined to the more academic language (https://twitter.com/anavinuela/status/1693602067741397190). Lot of scientists are still there. But I thought here I would try something a little bit different to avoid the jargon:
Full time Assistant / Associate #Teaching Professor. We seek broadly trained candidates with expertise in #biostatistics, teaching in #Rstats, experimental design and implementation. Areas of research focus could draw from #evolution, #genomics, sustainability sciences, conservation biology
Preprint from Salzberg team questioning a 2020 Nature paper from Rob Knight :O
"the raw read counts were vastly over-estimated for nearly every bacterial species, often by a factor of 1000 or more."
"Our conclusion after re-analysis is that the near-perfect association between microbes and cancer types reported in the study is, simply put, a fiction."
Major data analysis errors invalidate cancer microbiome findings
Some studies have reported COVID-19 vaccines can induce trained immunity, long term epigenetic reprogramming of innate immune cells. (akin to innate memory)
We tried to reproduce this but failed. Initially disappointing (I did a lot of ATAC-Seq analysis for this lol). But it ended up going into JCI (IF=19). Nice outcome!
No evidence of durable trained immunity after two doses of adenovirus-vectored or mRNA COVID-19 vaccines | JCI
Angela Pisco, head of computational biology at insitro, giving the keynote today at #SciPy2023. Talk title: How Open Source Tools Power the Efforts of Biological Data Analysis and Drug Discovery
Lots of interesting work on genomics, machine learning, and model benchmarking
The 5 pillar of computational reproducibility: Bioinformatics and beyond https://osf.io/4pd9n/
It is a review of computational best practices to ensure research projects can be reproducible decades into the future #Bioinformatics#Genomics#datascience
New #introduction since I'm parking over here at veganism dot social[1].
🎓 I'm a #PhD candidate in #HistSci and #STS (science & technology studies) at UW-Madison (that's the one in #Wisconsin, not Washington)
📚 I study how #data get used, shared, recombined, and abused in the sciences – current projects touch on #pollution regulation and social #genomics. I guess #opendata and #openscience are relevant tags here
✍️ I blog about some of the #books I'm #reading, each post ends with a #vegan recipe [2] :vegan:. Mostly these have been scholarly #history books, but I also read a lot of #SciFi / #SFF
📝 My day job/funding (proudly #union) is as an editorial assistant at Social Studies of Science[3]
[1] at least for the time being, as a #fedipact precautionary measure