Bon, on a vraisemblablement trouvé notre futur chez-nous dans la future ville #mutation
Et comme y’aura pas de periph-qui-fait-peur à franchir, je vais pouvoir velotafer. Youpi!
Yapluka chercher un vélo, électrique parce que le soir ça va monter fort
Des marques à éviter? #velo#velotaf
Some drugs increase the #mutation rate of their target #pathogen, raising the concerns they might increase the pathogen’s rate of adaptation. This #PLOSBiology Perspective proposes a four-step process to evaluate the evolutionary safety of new treatments.
'authors of a new study published in Science Advances have pinpointed a genetic variant that may have helped this population adapt to life at extraordinary heights. Tibetans in the Himalayas possess a different mutation in the same gene, suggesting both groups independently evolved similar adaptations to high-altitude living. The finding demonstrates “how evolution can sometimes favor common solutions to a common problem,” says Graham Scott, a physiologist at McMaster University who wasn’t involved in the study.'
This is fascinating. Everyone in the world with #blueEyes is descendant from one single #ancestor who lived about 10,000 years ago in modern-day #Ukraine. A single #genetic#mutation in the #gene that controls eye color is responsible for blue eyes. It functions by suppressing the ability of the #iris to produce #brown pigmentation.
I do not know enough about evolutionary biology or genetic mutation to have a sense of the applicability to this to people born to brown-eyed ancestrally homologous families who are the single solitary person to have blue eyes in their family for at least three or four generations. Grateful for evolutionary biologists out there to explain.
This may be a silly question, but with the understanding that virus genetics are contained within our own genome, is it possible for new viral genetics to be read/expressed as the original virus, causing the body to attack itself during early development? For example, a woman today has a viral infection, it affects one of her eggs, she becomes pregnant, and the fetus' immune system attacks the affected proteins causing it to fail to construct some vital organ. I would love to understand this more. #biology#virus#dna#rna#mutation#genetics#gene#protein#genome
Evolution doesn’t look how it’s depicted in pop culture. We often picture the famous “March of Progress” illustration where a series of apes stand in line leading to a modern human.
But evolution is not linear. It branches & divides without an intended direction or endpoint through natural selection.
Our new work on using #structural#bioinformatics to interpret #genomic variants observed in aged tissue is out! We present a software and statistical framework for analysing variants, and show how folding calculations can be used to classify #mutation types.
Developing uses for this in #cancer and prediction of clinical outcomes from genomic data!